SOX21_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SOX21_HUMAN
• UniProt AC: Q9Y651
• Protein Name: Transcription factor SOX-21
• Gene Name: SOX21
• Organism: Homo sapiens (Human).
• Sequence Length: 276
• Subcellular Localization: Nucleus .
• Protein Description: May play a role as an activator of transcription of OPRM1..
• Protein Sequence: MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGGGLVPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKMAEISSSSSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNCSAWPSPGLQPPLAYILLPGMGKPQLDPYPAAYAAAL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
19	Phosphorylation	MNAFMVWSRAQRRKM HHHHHHHHHHHHHHH	13.31	30631047
36	Phosphorylation	ENPKMHNSEISKRLG HCCCCCHHHHHHHHC	22.94	-
40	Acetylation	MHNSEISKRLGAEWK CCHHHHHHHHCHHHE	58.25	18585351
147	Methylation	AAAAAAARVFFPQSA HHHHHHHHHHCCHHH	22.50	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SOX21_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SOX21_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SOX21_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of SOX21_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.