dbPTM

SON_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SON_MOUSE
UniProt AC	Q9QX47
Protein Name	Protein SON
Gene Name	Son
Organism	Mus musculus (Mouse).
Sequence Length	2444
Subcellular Localization	Nucleus speckle . Colocalizes with the pre-mRNA splicing factor SRSF2.
Protein Description	RNA-binding protein that acts as a mRNA splicing cofactor by promoting efficient splicing of transcripts that possess weak splice sites. Specifically promotes splicing of many cell-cycle and DNA-repair transcripts that possess weak splice sites, such as TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A, and FANCG. Probably acts by facilitating the interaction between Serine/arginine-rich proteins such as SRSF2 and the RNA polymerase II. Also binds to DNA; binds to the consensus DNA sequence: 5'-GA[GT]AN[CG][AG]CC-3' (By similarity). Essential for correct RNA splicing of multiple genes critical for brain development, neuronal migration and metabolism, including TUBG1, FLNA, PNKP, WDR62, PSMD3, PCK2, PFKL, IDH2, and ACY1 (By similarity). May also regulate the ghrelin signaling in hypothalamic neuron by acting as a negative regulator of GHSR expression. [PubMed: 20876580]
Protein Sequence	MAADIEQVFRSFVVSKFREIQQELSSGRSEGQLNGETNPPIEGNQAGDTAASARSLPNEEIVQKIEEVLSGVLDTELRYKPDLKEASRKSRCVSVQTDPTDEVPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKLKSHHDGNLESDSFLKFDSEPSAAALEHPVRAFGLSEASETALVLEPPVVSMEVQESHVLETLKPATKAAELSVVSTSVISEQSEQPMPGMLEPSMTKILDSFTAAPVPMSTAALKSPEPVVTMSVEYQKSVLKSLETMPPETSKTTLVELPIAKVVEPSETLTIVSETPTEVHPEPSPSTMDFPESSTTDVQRLPEQPVEAPSEIADSSMTRPQESLELPKTTAVELQESTVASALELPGPPATSILELQGPPVTPVPELPGPSATPVPELSGPLSTPVPELPGPPATVVPELPGPSVTPVPQLSQELPGPPAPSMGLEPPQEVPEPPVMAQELSGVPAVSAAIELTGQPAVTVAMELTEQPVTTTEFEQPVAMTTVEHPGHPEVTTATGLLGQPEAAMVLELPGQPVATTALELSGQPSVTGVPELSGLPSATRALELSGQSVATGALELPGQLMATGALEFSGQSGAAGALELLGQPLATGVLELPGQPGAPELPGQPVATVALEISVQSVVTTSELSTMTVSQSLEVPSTTALESYNTVAQELPTTLVGETSVTVGVDPLMAQESHMLASNTMETHMLASNTMDSQMLASNTMDSQMLASNTMDSQMLASSTMDSQMLASSTMDSQMLATSTMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLASGAMDSQMLASGTMDAQMLASGTMDAQMLASSTQDSAMMGSKSPDPYRLAQDPYRLAQDPYRLGHDPYRLGHDAYRLGQDPYRLGHDPYRLTPDPYRVSPRPYRIAPRSYRIAPRPYRLAPRPLMLASRRSMMMSYAAERSMMSSYERSMMSYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSAADRSMMSSYTDRSMMSMAADSYTDSYTDSYTEAYMVPPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGPALSTEQSALTADNTWSTEVTLSTGESLSQPEPPVSQSEISEPMAVPANYSMSESETSMLASEAVMTVPEPAREPESSVTSAPVESAVVAEHEMVPERPMTYMVSETTMSVEPAVLTSEASVISETSETYDSMRPSGHAISEVTMSLLEPAVTISQPAENSLELPSMTVPAPSTMTTTESPVVAVTEIPPVAVPEPPIMAVPELPTMAVVKTPAVAVPEPLVAAPEPPTMATPELCSLSVSEPPVAVSELPALADPEHAITAVSGVSSLEPSVPILEPAVSVLQPVMIVSEPSVPVQEPTVAVSEPAVIVSEHTQITSPEMAVESSPVIVDSSVMSSQIMKGMNLLGGDENLGPEVGMQETLLHPGEEPRDGGHLKSDLYENEYDRNADLTVNSHLIVKDAEHNTVCATTVGPVGEASEEKILPISETKEITELATCAAVSEADIGRSLSSQLALELDTVGTSKGFEFVTASALISESKYDVEVSVTTQDTEHDMVISTSPSGGSEADIEGPLPAKDIHLDLPSTNFVCKDVEDSLPIKESAQAVAVALSPKESSEDTEVPLPNKEIVPESGYSASIDEINEADLVRPLLPKDMERLTSLRAGIEGPLLASEVERDKSAASPVVISIPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKAARARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSAVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIAQSKEDDDVIVNKPHVSDEEEEEPPFYHHPFKLSEPKPIFFNLNIAAAKPTPPKSQVTLTKEFPVSSGSQHRKKEADSVYGEWVPVEKNGEESKDDDNVFSSSLPSEPVDISTAMSERALAQKRLSENAFDLEAMSMLNRAQERIDAWAQLNSIPGQFTGSTGVQVLTQEQLANTGAQAWIKKDQFLRAAPVTGGMGAVLMRKMGWREGEGLGKNKEGNKEPILVDFKTDRKGLVAVGERAQKRSGNFSAAMKDLSGKHPVSALMEICNKRRWQPPEFLLVHDSGPDHRKHFLFRVLRNGSPYQPNCMFFLNRY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAADIEQVF ------CCCHHHHHH	25.75	-
16	Acetylation	FRSFVVSKFREIQQE HHHHHHHHHHHHHHH	36.51	23806337
16	Ubiquitination	FRSFVVSKFREIQQE HHHHHHHHHHHHHHH	36.51	22790023
55	Phosphorylation	DTAASARSLPNEEIV CCHHHHCCCCCHHHH	48.14	27841257
90	Phosphorylation	LKEASRKSRCVSVQT HHHHHHHHCCEECCC	29.78	26745281
94	Phosphorylation	SRKSRCVSVQTDPTD HHHHCCEECCCCCCC	16.48	25521595
97	Phosphorylation	SRCVSVQTDPTDEVP HCCEECCCCCCCCCC	41.62	25619855
100	Phosphorylation	VSVQTDPTDEVPTKK EECCCCCCCCCCCHH	47.83	25619855
105	Phosphorylation	DPTDEVPTKKSKKHK CCCCCCCCHHHHHHH	57.17	25619855
142	Phosphorylation	ESESKLKSHHDGNLE HHHHHHHHCCCCCCC	36.17	25619855
150	Phosphorylation	HHDGNLESDSFLKFD CCCCCCCCCCEEECC	41.54	25619855
152	Phosphorylation	DGNLESDSFLKFDSE CCCCCCCCEEECCCC	41.58	25619855
158	Phosphorylation	DSFLKFDSEPSAAAL CCEEECCCCCCHHHH	55.32	26643407
241	Phosphorylation	SMTKILDSFTAAPVP HHHHHHHHHCCCCCC	22.50	26239621
243	Phosphorylation	TKILDSFTAAPVPMS HHHHHHHCCCCCCCC	26.34	26239621
250	O-linked_Glycosylation	TAAPVPMSTAALKSP CCCCCCCCCCHHCCC	14.61	30059200
250	Phosphorylation	TAAPVPMSTAALKSP CCCCCCCCCCHHCCC	14.61	26239621
251	O-linked_Glycosylation	AAPVPMSTAALKSPE CCCCCCCCCHHCCCC	15.08	55413997
251	Phosphorylation	AAPVPMSTAALKSPE CCCCCCCCCHHCCCC	15.08	26239621
256	Phosphorylation	MSTAALKSPEPVVTM CCCCHHCCCCCEEEE	35.03	25521595
262	Phosphorylation	KSPEPVVTMSVEYQK CCCCCEEEEEHHHHH	12.17	26745281
264	Phosphorylation	PEPVVTMSVEYQKSV CCCEEEEEHHHHHHH	11.48	26745281
267	Phosphorylation	VVTMSVEYQKSVLKS EEEEEHHHHHHHHHH	21.05	26745281
273	Acetylation	EYQKSVLKSLETMPP HHHHHHHHHHHCCCC	51.33	22826441
284	Acetylation	TMPPETSKTTLVELP CCCCCCCCCEEEEEE	53.61	-
299	Phosphorylation	IAKVVEPSETLTIVS CEEEECCCCCEEEEE	29.70	25619855
301	Phosphorylation	KVVEPSETLTIVSET EEECCCCCEEEEECC	33.27	25619855
303	Phosphorylation	VEPSETLTIVSETPT ECCCCCEEEEECCCC	27.10	25619855
306	Phosphorylation	SETLTIVSETPTEVH CCCEEEEECCCCCCC	31.72	25619855
308	Phosphorylation	TLTIVSETPTEVHPE CEEEEECCCCCCCCC	28.18	25619855
310	Phosphorylation	TIVSETPTEVHPEPS EEEECCCCCCCCCCC	59.04	25619855
317	Phosphorylation	TEVHPEPSPSTMDFP CCCCCCCCCCCCCCC	29.80	22802335
319	Phosphorylation	VHPEPSPSTMDFPES CCCCCCCCCCCCCCC	40.47	20469934
320	Phosphorylation	HPEPSPSTMDFPESS CCCCCCCCCCCCCCC	24.92	25619855
326	Phosphorylation	STMDFPESSTTDVQR CCCCCCCCCCCCHHH	32.97	25619855
327	Phosphorylation	TMDFPESSTTDVQRL CCCCCCCCCCCHHHC	33.39	25619855
328	Phosphorylation	MDFPESSTTDVQRLP CCCCCCCCCCHHHCC	35.97	25619855
329	Phosphorylation	DFPESSTTDVQRLPE CCCCCCCCCHHHCCC	35.80	25619855
395	Phosphorylation	ELQGPPVTPVPELPG EECCCCCCCCCCCCC	25.09	-
905	Phosphorylation	SAMMGSKSPDPYRLA HHHCCCCCCCHHHHC	35.91	25159016
944	Phosphorylation	YRLGQDPYRLGHDPY HHCCCCCCCCCCCCC	27.10	22499769
945	Methylation	RLGQDPYRLGHDPYR HCCCCCCCCCCCCCC	39.31	-
951	Phosphorylation	YRLGHDPYRLTPDPY CCCCCCCCCCCCCCC	25.06	22499769
954	Phosphorylation	GHDPYRLTPDPYRVS CCCCCCCCCCCCCCC	19.35	21743459
958	Phosphorylation	YRLTPDPYRVSPRPY CCCCCCCCCCCCCCC	30.90	26643407
961	Phosphorylation	TPDPYRVSPRPYRIA CCCCCCCCCCCCCCC	13.24	26643407
965	Phosphorylation	YRVSPRPYRIAPRSY CCCCCCCCCCCCCCE	18.87	26643407
971	Phosphorylation	PYRIAPRSYRIAPRP CCCCCCCCEECCCCC	20.08	19854140
972	Phosphorylation	YRIAPRSYRIAPRPY CCCCCCCEECCCCCC	13.81	19854140
993	Phosphorylation	LMLASRRSMMMSYAA HHHHHHHHHHHHHHH	15.21	25521595
1002	Asymmetric dimethylarginine	MMSYAAERSMMSSYE HHHHHHHHHHHHHHH	25.73	-
1002	Methylation	MMSYAAERSMMSSYE HHHHHHHHHHHHHHH	25.73	24129315
1010	Methylation	SMMSSYERSMMSYER HHHHHHHHHHHHHHH	22.94	30761117
1011	Phosphorylation	MMSSYERSMMSYERS HHHHHHHHHHHHHHH	13.59	29895711
1014	Phosphorylation	SYERSMMSYERSMMS HHHHHHHHHHHHHCC	18.39	29895711
1015	Phosphorylation	YERSMMSYERSMMSP HHHHHHHHHHHHCCH	9.47	29895711
1017	Asymmetric dimethylarginine	RSMMSYERSMMSPMA HHHHHHHHHHCCHHH	22.94	-
1017	Methylation	RSMMSYERSMMSPMA HHHHHHHHHHCCHHH	22.94	24129315
1018	Phosphorylation	SMMSYERSMMSPMAE HHHHHHHHHCCHHHH	13.59	23527152
1021	Phosphorylation	SYERSMMSPMAERSM HHHHHHCCHHHHHHH	11.68	25521595
1027	Phosphorylation	MSPMAERSMMSAYER CCHHHHHHHHHHHHH	15.44	29895711
1030	Phosphorylation	MAERSMMSAYERSMM HHHHHHHHHHHHHHH	21.03	29895711
1032	Phosphorylation	ERSMMSAYERSMMSA HHHHHHHHHHHHHHH	12.45	29895711
1038	Phosphorylation	AYERSMMSAYERSMM HHHHHHHHHHHHHCC	21.03	-
1043	Phosphorylation	MMSAYERSMMSPMAE HHHHHHHHCCCHHHH	13.59	23527152
1046	Phosphorylation	AYERSMMSPMAERSM HHHHHCCCHHHHHHH	11.68	25521595
1055	Phosphorylation	MAERSMMSAYERSMM HHHHHHHHHHHHHHH	21.03	-
1063	Phosphorylation	AYERSMMSAYERSMM HHHHHHHHHHHHHCC	21.03	-
1068	Phosphorylation	MMSAYERSMMSPMAD HHHHHHHHCCCCCCC	13.59	23527152
1071	Phosphorylation	AYERSMMSPMADRSM HHHHHCCCCCCCHHH	11.68	25521595
1077	Phosphorylation	MSPMADRSMMSMGAD CCCCCCHHHHHCCCC	21.27	-
1567	Phosphorylation	NADLTVNSHLIVKDA CCCCEECCEEEECCC	18.48	25338131
1605	Phosphorylation	ISETKEITELATCAA CCCCCHHHHHHHHHH	26.49	27600695
1609	Phosphorylation	KEITELATCAAVSEA CHHHHHHHHHHHCHH	18.46	27600695
1621	Phosphorylation	SEADIGRSLSSQLAL CHHHHCCCHHHHHHH	27.65	25159016
1623	Phosphorylation	ADIGRSLSSQLALEL HHHCCCHHHHHHHEE	19.79	25159016
1624	Phosphorylation	DIGRSLSSQLALELD HHCCCHHHHHHHEEC	34.21	27600695
1653	Phosphorylation	ALISESKYDVEVSVT HHEECCCCEEEEEEE	34.20	27087446
1673	Phosphorylation	HDMVISTSPSGGSEA CCEEEEECCCCCCCC	15.41	27087446
1674	Phosphorylation	DMVISTSPSGGSEAD CEEEEECCCCCCCCC	36.76	17242355
1675	Phosphorylation	MVISTSPSGGSEADI EEEEECCCCCCCCCC	56.40	27087446
1678	Phosphorylation	STSPSGGSEADIEGP EECCCCCCCCCCCCC	32.89	-
1683	Phosphorylation	GGSEADIEGPLPAKD CCCCCCCCCCCCCCE	56.13	19144319
1708	Phosphorylation	VCKDVEDSLPIKESA EECCHHHCCCCHHHH	23.65	25619855
1714	Phosphorylation	DSLPIKESAQAVAVA HCCCCHHHHHEEEEE	22.22	24925903
1723	Phosphorylation	QAVAVALSPKESSED HEEEEEECCCCCCCC	24.96	27087446
1727	Phosphorylation	VALSPKESSEDTEVP EEECCCCCCCCCCCC	45.19	26824392
1728	Phosphorylation	ALSPKESSEDTEVPL EECCCCCCCCCCCCC	40.35	25521595
1731	Phosphorylation	PKESSEDTEVPLPNK CCCCCCCCCCCCCCC	34.53	23984901
1744	Phosphorylation	NKEIVPESGYSASID CCCCCCCCCCCCCHH	36.64	23984901
1746	Phosphorylation	EIVPESGYSASIDEI CCCCCCCCCCCHHCC	15.44	23984901
1747	Phosphorylation	IVPESGYSASIDEIN CCCCCCCCCCHHCCC	21.04	26745281
1749	Phosphorylation	PESGYSASIDEINEA CCCCCCCCHHCCCHH	25.32	30352176
1769	Phosphorylation	LLPKDMERLTSLRAG CCCHHHHHHHHHHCC	36.31	17242355
1772	Phosphorylation	KDMERLTSLRAGIEG HHHHHHHHHHCCCCC	22.05	29514104
1784	Phosphorylation	IEGPLLASEVERDKS CCCCCHHHHHCCCCC	41.99	27600695
1791	Phosphorylation	SEVERDKSAASPVVI HHHCCCCCCCCCEEE	33.10	23527152
1794	Phosphorylation	ERDKSAASPVVISIP CCCCCCCCCEEEECC	20.24	25521595
1799	Phosphorylation	AASPVVISIPERASE CCCCEEEECCCCCCC	22.08	23375375
1805	Phosphorylation	ISIPERASESSSEEK EECCCCCCCCCCCCC	44.20	27742792
1807	Phosphorylation	IPERASESSSEEKDD CCCCCCCCCCCCCCC	36.35	27087446
1808	Phosphorylation	PERASESSSEEKDDY CCCCCCCCCCCCCCE	37.40	27087446
1809	Phosphorylation	ERASESSSEEKDDYE CCCCCCCCCCCCCEE	60.08	27742792
1815	Phosphorylation	SSEEKDDYEIFVKVK CCCCCCCEEEEEEEH	22.51	25619855
1845	Phosphorylation	EKEKKRDSSLRSRSK HHHHHHHHHHHHHHH	34.99	19367708
1846	Phosphorylation	KEKKRDSSLRSRSKR HHHHHHHHHHHHHHH	31.90	19367708
1849	Phosphorylation	KRDSSLRSRSKRSKS HHHHHHHHHHHHHCC	46.31	19367708
1868	Phosphorylation	SRKRTSESRSRARKR HHHHHHHHHHHHHHH	35.01	-
1898	Phosphorylation	RSRRRRRSSRSRSKS HHHHHHHHHHHHHHH	28.43	20531401
1899	Phosphorylation	SRRRRRSSRSRSKSR HHHHHHHHHHHHHHH	32.25	19854140
1901	Phosphorylation	RRRRSSRSRSKSRGR HHHHHHHHHHHHHCC	42.74	20531401
1933	Phosphorylation	SRERKRKRSSSRDNR HHHHHHHHHCHHHHH	45.89	17242355
1934	Phosphorylation	RERKRKRSSSRDNRK HHHHHHHHCHHHHHH	35.38	22871156
1935	Phosphorylation	ERKRKRSSSRDNRKA HHHHHHHCHHHHHHH	33.16	17242355
1936	Phosphorylation	RKRKRSSSRDNRKAA HHHHHHCHHHHHHHH	44.92	22871156
1939	Phosphorylation	KRSSSRDNRKAARAR HHHCHHHHHHHHHHH	46.36	17242355
1947	Phosphorylation	RKAARARSRTPSRRS HHHHHHHHCCCCHHH	39.25	23737553
1949	Phosphorylation	AARARSRTPSRRSRS HHHHHHCCCCHHHCC	27.19	23737553
1951	Phosphorylation	RARSRTPSRRSRSHT HHHHCCCCHHHCCCC	39.45	23737553
1954	Phosphorylation	SRTPSRRSRSHTPSR HCCCCHHHCCCCCCH	36.70	28066266
1956	Phosphorylation	TPSRRSRSHTPSRRR CCCHHHCCCCCCHHH	32.72	28066266
1958	Phosphorylation	SRRSRSHTPSRRRRS CHHHCCCCCCHHHCC	24.98	28066266
1960	Phosphorylation	RSRSHTPSRRRRSRS HHCCCCCCHHHCCCC	39.30	28066266
1965	Phosphorylation	TPSRRRRSRSVGRRR CCCHHHCCCCCCCCC	27.39	23737553
1967	Phosphorylation	SRRRRSRSVGRRRSF CHHHCCCCCCCCCCC	30.12	23737553
1973	Phosphorylation	RSVGRRRSFSISPSR CCCCCCCCCCCCCCC	22.87	27742792
1975	Phosphorylation	VGRRRSFSISPSRRS CCCCCCCCCCCCCCC	24.33	23684622
1977	Phosphorylation	RRRSFSISPSRRSRT CCCCCCCCCCCCCCC	18.67	27742792
1979	Phosphorylation	RSFSISPSRRSRTPS CCCCCCCCCCCCCCC	33.27	23684622
1982	Phosphorylation	SISPSRRSRTPSRRS CCCCCCCCCCCCCCC	39.12	23737553
1984	Phosphorylation	SPSRRSRTPSRRSRT CCCCCCCCCCCCCCC	27.19	23737553
1986	Phosphorylation	SRRSRTPSRRSRTPS CCCCCCCCCCCCCCC	39.45	23737553
1989	Phosphorylation	SRTPSRRSRTPSRRS CCCCCCCCCCCCCCC	39.12	23737553
1991	Phosphorylation	TPSRRSRTPSRRSRT CCCCCCCCCCCCCCC	27.19	23737553
1993	Phosphorylation	SRRSRTPSRRSRTPS CCCCCCCCCCCCCCC	39.45	23737553
1996	Phosphorylation	SRTPSRRSRTPSRRS CCCCCCCCCCCCCCC	39.12	23737553
1998	Phosphorylation	TPSRRSRTPSRRSRT CCCCCCCCCCCCCCC	27.19	23737553
2000	Phosphorylation	SRRSRTPSRRSRTPS CCCCCCCCCCCCCCC	39.45	23737553
2003	Phosphorylation	SRTPSRRSRTPSRRS CCCCCCCCCCCCCCC	39.12	23737553
2005	Phosphorylation	TPSRRSRTPSRRSRT CCCCCCCCCCCCCCC	27.19	23737553
2007	Phosphorylation	SRRSRTPSRRSRTPS CCCCCCCCCCCCCCC	39.45	23737553
2010	Phosphorylation	SRTPSRRSRTPSRRR CCCCCCCCCCCCHHH	39.12	23737553
2012	Phosphorylation	TPSRRSRTPSRRRRS CCCCCCCCCCHHHHH	27.19	23737553
2014	Phosphorylation	SRRSRTPSRRRRSRS CCCCCCCCHHHHHHH	37.49	23737553
2019	Phosphorylation	TPSRRRRSRSAVRRR CCCHHHHHHHHHHHH	28.86	23737553
2021	Phosphorylation	SRRRRSRSAVRRRSF CHHHHHHHHHHHHCC	32.15	23737553
2027	Phosphorylation	RSAVRRRSFSISPVR HHHHHHHCCCCCCHH	22.87	27087446
2029	Phosphorylation	AVRRRSFSISPVRLR HHHHHCCCCCCHHHH	24.33	27087446
2031	Phosphorylation	RRRSFSISPVRLRRS HHHCCCCCCHHHHCC	19.02	27087446
2038	Phosphorylation	SPVRLRRSRTPLRRR CCHHHHCCCCCHHHH	33.79	25159016
2040	Phosphorylation	VRLRRSRTPLRRRFS HHHHCCCCCHHHHHC	28.11	25159016
2047	Phosphorylation	TPLRRRFSRSPIRRK CCHHHHHCCCCCCCC	30.00	23684622
2049	Phosphorylation	LRRRFSRSPIRRKRS HHHHHCCCCCCCCHH	24.39	26824392
2064	Phosphorylation	RSSERGRSPKRLTDL CCCCCCCCCCCCCCC	37.28	-
2069	Phosphorylation	GRSPKRLTDLDKAQL CCCCCCCCCCCHHHH	38.25	-
2073	Acetylation	KRLTDLDKAQLLEIA CCCCCCCHHHHHHHH	45.38	23806337
2115	Phosphorylation	EEKVAKKSGGATIEE HHHHHHHCCCCCHHH	41.58	27841257
2133	Phosphorylation	KCKQIAQSKEDDDVI HHHHHHHCCCCCCEE	29.05	25159016
2147	Phosphorylation	IVNKPHVSDEEEEEP EECCCCCCCCCCCCC	35.95	25521595
2157	Phosphorylation	EEEEPPFYHHPFKLS CCCCCCCCCCCCCCC	12.66	25159016
2181	Phosphorylation	NIAAAKPTPPKSQVT EEEECCCCCCCHHEE	52.06	26643407
2191	Acetylation	KSQVTLTKEFPVSSG CHHEEEEEEECCCCC	61.54	22826441
2196	Phosphorylation	LTKEFPVSSGSQHRK EEEEECCCCCCHHCC	29.26	29176673
2197	Phosphorylation	TKEFPVSSGSQHRKK EEEECCCCCCHHCCH	42.57	29176673
2199	Phosphorylation	EFPVSSGSQHRKKEA EECCCCCCHHCCHHH	25.43	29176673
2225 (in isoform 4)	Phosphorylation	-	77.20	27149854
2256	Phosphorylation	ALAQKRLSENAFDLE HHHHHHHCCCCCCHH	32.60	20876580
2260 (in isoform 4)	Phosphorylation	-	19.44	26643407
2266	Phosphorylation	AFDLEAMSMLNRAQE CCCHHHHHHHHHHHH	27.45	26745281
2375	Phosphorylation	GERAQKRSGNFSAAM HHHHHHHCCCHHHHH	45.16	22942356
2388	Acetylation	AMKDLSGKHPVSALM HHHHHCCCCCHHHHH	41.16	22826441
2431	Phosphorylation	FRVLRNGSPYQPNCM HHHHHCCCCCCCCCE	24.79	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SON_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SON_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SON_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of SON_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SON_MOUSE

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"The phagosomal proteome in interferon-gamma-activated macrophages."; Trost M., English L., Lemieux S., Courcelles M., Desjardins M.,Thibault P.; Immunity 30:143-154(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1723, AND MASSSPECTROMETRY.	19144319 [Abstract]
"Solid tumor proteome and phosphoproteome analysis by high resolutionmass spectrometry."; Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J.,Faessler R., Mann M.; J. Proteome Res. 7:5314-5326(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1845; SER-1846;SER-1849; SER-1973; SER-1975; SER-1979; SER-2027; SER-2029 ANDSER-2031, AND MASS SPECTROMETRY.	19367708 [Abstract]
"Large-scale phosphorylation analysis of mouse liver."; Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1714; SER-1809;SER-1973; SER-1975 AND SER-1979, AND MASS SPECTROMETRY.	17242355 [Abstract]