SOBP_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SOBP_MOUSE
• UniProt AC: Q0P5V2
• Protein Name: Sine oculis-binding protein homolog
• Gene Name: Sobp {ECO:0000312|MGI:MGI:1924427}
• Organism: Mus musculus (Mouse).
• Sequence Length: 864
• Protein Description: Implicated in development of the cochlea..
• Protein Sequence: MAEMEKEGRPPENKRSRKPAHPVKREINEEMKNFAENTMNELLGWYGYDKVELKDGEDIEFRSYTTDGESRQHISVLKENSLPKPKLPEDSVISSYNISTGYSGLATGNGLSDSPAGSKDHGNVPIIVPLIPPPFIKPPAEDDVSNVQIMCAWCQKVGIKRYSLSMGSEVKSFCSEKCFAACRRAYFKRNKARDEDGRAETFPQQHYAKETPRLAFKNNCELLVCDWCKHIRHTKEYLDFGDGERRLQFCSAKCLNQYKMDIFYKETQANLPAGLCSTLHPHMESKAEGTGVQLLTPDSWNIPLTDARRKAPSPVTAAGQSQGPGPSSSTTVSPSDTANCSVTKIPTPVPKSLPISETPSIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIIQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGAPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVNDSKPPNGFSSNGESFVPSAPGDSSAAGGKAGGRSLSPRDSKQGSSKSADSPPGSSGQALSLAPAERGRGEVVDLTRRAGSPAGAGGQPGFAGVLHGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPGAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRSAPAEAKGAEPPPEQPPPPAPPKKLLSSEEPVVNELESVKENNCASNCHLDGEATKKLMGEEALAGGDKSDPNLNNPADEDHAYALRMLPKTGCVIQPVPKPAEKAAMTPCVISSPMLSAGPEDLEPPLKRRCLRIRNQNK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
313	Phosphorylation	DARRKAPSPVTAAGQ CCCHHCCCCCCCCCC	36.54	25521595
316	Phosphorylation	RKAPSPVTAAGQSQG HHCCCCCCCCCCCCC	17.74	28066266
321	Phosphorylation	PVTAAGQSQGPGPSS CCCCCCCCCCCCCCC	35.87	26160508
327	Phosphorylation	QSQGPGPSSSTTVSP CCCCCCCCCCCCCCC	42.72	26160508
328	Phosphorylation	SQGPGPSSSTTVSPS CCCCCCCCCCCCCCC	34.53	26160508
329	Phosphorylation	QGPGPSSSTTVSPSD CCCCCCCCCCCCCCC	32.22	26160508
330	Phosphorylation	GPGPSSSTTVSPSDT CCCCCCCCCCCCCCC	32.91	26160508
331	Phosphorylation	PGPSSSTTVSPSDTA CCCCCCCCCCCCCCC	22.42	26160508
333	Phosphorylation	PSSSTTVSPSDTANC CCCCCCCCCCCCCCC	19.32	26160508
335	Phosphorylation	SSTTVSPSDTANCSV CCCCCCCCCCCCCEE	39.84	26160508
337	Phosphorylation	TTVSPSDTANCSVTK CCCCCCCCCCCEEEE	24.90	26160508
341	Phosphorylation	PSDTANCSVTKIPTP CCCCCCCEEEECCCC	32.40	26160508
343	Phosphorylation	DTANCSVTKIPTPVP CCCCCEEEECCCCCC	13.63	26160508
347	Phosphorylation	CSVTKIPTPVPKSLP CEEEECCCCCCCCCC	40.15	26160508
420	Phosphorylation	RGPPHHASNPNSPLS CCCCCCCCCCCCCCC	48.76	25367039
424	Phosphorylation	HHASNPNSPLSNPML CCCCCCCCCCCCCCC	28.60	25367039
427	Phosphorylation	SNPNSPLSNPMLPGI CCCCCCCCCCCCCCC	42.12	25367039
457	Phosphorylation	PMHRPMLSPHIHPPS CCCCCCCCCCCCCCC	14.26	-
581	Phosphorylation	GGKAGGRSLSPRDSK CCCCCCCCCCCCCCC	36.15	21743459
583	Phosphorylation	KAGGRSLSPRDSKQG CCCCCCCCCCCCCCC	21.09	21454597
594	Phosphorylation	SKQGSSKSADSPPGS CCCCCCCCCCCCCCC	38.98	30372032
597	Phosphorylation	GSSKSADSPPGSSGQ CCCCCCCCCCCCCCC	32.48	25521595
601	Phosphorylation	SADSPPGSSGQALSL CCCCCCCCCCCCCCC	36.75	26160508
602	Phosphorylation	ADSPPGSSGQALSLA CCCCCCCCCCCCCCC	40.62	26160508
607	Phosphorylation	GSSGQALSLAPAERG CCCCCCCCCCCCCCC	26.04	26160508
627	Phosphorylation	DLTRRAGSPAGAGGQ ECHHHCCCCCCCCCC	15.59	25521595
694	Phosphorylation	GCRDGHCSPPAAGDP CCCCCCCCCCCCCCC	28.39	25521595
750	Phosphorylation	APPKKLLSSEEPVVN CCCCCCCCCCCCHHH	46.25	29899451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SOBP_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SOBP_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SOBP_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of SOBP_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.