SO5A1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SO5A1_HUMAN
• UniProt AC: Q9H2Y9
• Protein Name: Solute carrier organic anion transporter family member 5A1
• Gene Name: SLCO5A1
• Organism: Homo sapiens (Human).
• Sequence Length: 848
• Subcellular Localization: Cell membrane; Multi-pass membrane protein.
• Protein Sequence: MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPAFGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCLYVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQRRRQREFPLSTVSERVGHPDNARTRSCPAFSTQGEFHEETGLQKGIQCAAQTYPGPFPEAISSSADPGLEESPAALEPPS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
32	Phosphorylation	QERCEPETLRSKSLP HHHCCHHHHHCCCCC	37.88	24719451
125	Phosphorylation	RCLYVVLTDSRCFLV CCEEEEECCHHHHHH	21.96	30631047
161	Phosphorylation	TTIERRYSLKSSESG HHHHHHHCCCCCCCC	27.75	24719451
228	N-linked_Glycosylation	PYQIQELNASAPNDG CCCHHHHCCCCCCCC	30.97	UniProtKB CARBOHYD
241	N-linked_Glycosylation	DGLCQGGNSTATLEP CCCCCCCCCCCCCCC	42.91	UniProtKB CARBOHYD
298	Phosphorylation	DNVKKENSSLYLAIM CCCCCCCHHHHHHHH	23.86	-
299	Phosphorylation	NVKKENSSLYLAIMY CCCCCCHHHHHHHHH	32.39	-
385	Phosphorylation	KKKKKKFSVDAVSDD CCCCCCCCCCCCCCH	28.15	30108239
390	Phosphorylation	KFSVDAVSDDDVLKE CCCCCCCCCHHHHHH	36.72	30108239
426 (in isoform 2)	Phosphorylation	-	3.69	-
436 (in isoform 2)	Phosphorylation	-	2.83	-
469	N-linked_Glycosylation	QFGIPASNASIYTGV HHCCCCCCCEEEEEE	39.55	UniProtKB CARBOHYD
473	Phosphorylation	PASNASIYTGVIIVP CCCCCEEEEEEEEEC	8.57	18452278
474	Phosphorylation	ASNASIYTGVIIVPS CCCCEEEEEEEEECC	24.25	18452278
481	Phosphorylation	TGVIIVPSAGVGIVL EEEEEECCCCCCEEC	27.10	18452278
491	Phosphorylation	VGIVLGGYIIKKLKL CCEECCHHHHHHHCC	9.55	18452278
550	N-linked_Glycosylation	SLTMPHRNLTGSCNV CCCCCCCCCCCCCCC	38.63	UniProtKB CARBOHYD
590	N-linked_Glycosylation	AGCVNSGNLSTGIRN HHHHCCCCCCCCCCC	30.55	UniProtKB CARBOHYD
597	N-linked_Glycosylation	NLSTGIRNYTECTCV CCCCCCCCCCCCEEE	46.27	UniProtKB CARBOHYD
614	Phosphorylation	RQVITPPTVGQRSQL CEEECCCCCCCCCEE	38.17	23403867
628	Phosphorylation	LRVVIVKTYLNENGY EEEEEEEEEECCCCC	23.50	-
647	Phosphorylation	KCKRTCNTLIPFLVF CCHHHHHHHHHHHHH	28.36	-
730	N-linked_Glycosylation	QGSCWEYNVTSFRFV CCCEEEEECCEEEHH	21.05	UniProtKB CARBOHYD
759	Phosphorylation	FIFLAWYSIKYKEDG HHHHHHHHHHCHHHH	11.25	24719451
778	Phosphorylation	RQREFPLSTVSERVG HHCCCCCCHHHHHCC	27.31	-
781	Phosphorylation	EFPLSTVSERVGHPD CCCCCHHHHHCCCCC	21.55	-
792	Phosphorylation	GHPDNARTRSCPAFS CCCCCCCCCCCCCCC	25.23	30108239
794	Phosphorylation	PDNARTRSCPAFSTQ CCCCCCCCCCCCCCC	24.68	30108239
799	Phosphorylation	TRSCPAFSTQGEFHE CCCCCCCCCCCCCCH	23.17	30108239
800	Phosphorylation	RSCPAFSTQGEFHEE CCCCCCCCCCCCCHH	33.85	30108239

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SO5A1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SO5A1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SO5A1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of SO5A1_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.