UniProt ID | SNX8_MOUSE | |
---|---|---|
UniProt AC | Q8CFD4 | |
Protein Name | Sorting nexin-8 | |
Gene Name | Snx8 | |
Organism | Mus musculus (Mouse). | |
Sequence Length | 459 | |
Subcellular Localization |
Early endosome membrane Peripheral membrane protein Cytoplasmic side. Colocalizes with retromer components.. |
|
Protein Description | May be involved in several stages of intracellular trafficking. May play a role in intracellular protein transport from early endosomes to the trans-Golgi network (By similarity).. | |
Protein Sequence | MTGRAMDPLPSPAVAAAAEAEADEEADPPATGPRTSQVTEWRALDPGRMQMPQGNPLLLSYTLQELLAKDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFHEVLLHKFPYRMVPALPPKRVLGADREFIEGRRRALKRFINLVARHPPFSEDVLLKLFLSFSGSDVQHKLKEAAQCVGDEFMNCKLAARAKDFLPADIQTQFAMSRELIRNVYNSFYKLRDRAERIASRAIDNAADLLIFGKELSALGSDTTPLPSWAALHLSTWGSLKQALKGLSVEFALLADRAAQQGKKEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYGLMKRQMMSAAHGREPESVEQLESRIVEQENVIQTMELRNYFSLYCLHQETQLVHVYLPLTSHILGAFVNSQIQGHKEMSKVWNDLKPKLSCLFAGPHSVLTPPRSPQEDGVCPH | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
99 | Phosphorylation | VSSQRFKSSVYRRYN ECCHHHHHHHHHHHC | 23.48 | 22871156 | |
196 | Ubiquitination | GDEFMNCKLAARAKD CHHHHHCHHHHHCHH | 35.84 | 22790023 | |
425 | Acetylation | QGHKEMSKVWNDLKP HCHHHHHHHHHHHHH | 50.38 | 7719755 | |
435 | Phosphorylation | NDLKPKLSCLFAGPH HHHHHHHEEEECCCC | 18.20 | 25159016 | |
443 | Phosphorylation | CLFAGPHSVLTPPRS EEECCCCCCCCCCCC | 23.19 | 25159016 | |
446 | Phosphorylation | AGPHSVLTPPRSPQE CCCCCCCCCCCCCCC | 29.14 | 26824392 | |
450 | Phosphorylation | SVLTPPRSPQEDGVC CCCCCCCCCCCCCCC | 36.39 | 26824392 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SNX8_MOUSE !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SNX8_MOUSE !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SNX8_MOUSE !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
Oops, there are no PPI records of SNX8_MOUSE !! |
Kegg Drug | ||||||
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DrugBank | ||||||
There are no disease associations of PTM sites. |
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