SNX8_MOUSE - dbPTM
SNX8_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SNX8_MOUSE
UniProt AC Q8CFD4
Protein Name Sorting nexin-8
Gene Name Snx8
Organism Mus musculus (Mouse).
Sequence Length 459
Subcellular Localization Early endosome membrane
Peripheral membrane protein
Cytoplasmic side. Colocalizes with retromer components..
Protein Description May be involved in several stages of intracellular trafficking. May play a role in intracellular protein transport from early endosomes to the trans-Golgi network (By similarity)..
Protein Sequence MTGRAMDPLPSPAVAAAAEAEADEEADPPATGPRTSQVTEWRALDPGRMQMPQGNPLLLSYTLQELLAKDTVQVELIPEKKGLFLKHVEYEVSSQRFKSSVYRRYNDFVVFHEVLLHKFPYRMVPALPPKRVLGADREFIEGRRRALKRFINLVARHPPFSEDVLLKLFLSFSGSDVQHKLKEAAQCVGDEFMNCKLAARAKDFLPADIQTQFAMSRELIRNVYNSFYKLRDRAERIASRAIDNAADLLIFGKELSALGSDTTPLPSWAALHLSTWGSLKQALKGLSVEFALLADRAAQQGKKEENDVVEKLNLFLDLLQSYKDLCERHEKGVLHKHQRALHKYGLMKRQMMSAAHGREPESVEQLESRIVEQENVIQTMELRNYFSLYCLHQETQLVHVYLPLTSHILGAFVNSQIQGHKEMSKVWNDLKPKLSCLFAGPHSVLTPPRSPQEDGVCPH
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
99PhosphorylationVSSQRFKSSVYRRYN
ECCHHHHHHHHHHHC
23.4822871156
196UbiquitinationGDEFMNCKLAARAKD
CHHHHHCHHHHHCHH
35.8422790023
425AcetylationQGHKEMSKVWNDLKP
HCHHHHHHHHHHHHH
50.387719755
435PhosphorylationNDLKPKLSCLFAGPH
HHHHHHHEEEECCCC
18.2025159016
443PhosphorylationCLFAGPHSVLTPPRS
EEECCCCCCCCCCCC
23.1925159016
446PhosphorylationAGPHSVLTPPRSPQE
CCCCCCCCCCCCCCC
29.1426824392
450PhosphorylationSVLTPPRSPQEDGVC
CCCCCCCCCCCCCCC
36.3926824392

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SNX8_MOUSE !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SNX8_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SNX8_MOUSE !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of SNX8_MOUSE !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SNX8_MOUSE

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Related Literatures of Post-Translational Modification

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