| UniProt ID | SNP25_CHICK | |
|---|---|---|
| UniProt AC | P60878 | |
| Protein Name | Synaptosomal-associated protein 25 | |
| Gene Name | SNAP25 | |
| Organism | Gallus gallus (Chicken). | |
| Sequence Length | 206 | |
| Subcellular Localization |
Membrane Lipid-anchor. Cell junction, synapse, synaptosome. Cell membrane . Membrane association requires palmitoylation.. |
|
| Protein Description | t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion (By similarity).. | |
| Protein Sequence | MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNLTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 85 | S-palmitoylation | LTDLGKFCGLCVCPC HHHHHHHCCEEEECC | 4.66 | - | |
| 88 | S-palmitoylation | LGKFCGLCVCPCNKL HHHHCCEEEECCCCC | 1.47 | - | |
| 90 | S-palmitoylation | KFCGLCVCPCNKLKS HHCCEEEECCCCCCC | 2.87 | - | |
| 92 | S-palmitoylation | CGLCVCPCNKLKSSD CCEEEECCCCCCCCH | 6.24 | - | |
| 138 | Phosphorylation | GGFIRRVTNDARENE CCHHHHHCCCHHHHH | 26.10 | 14766180 | |
| 187 | Phosphorylation | RIMEKADSNKTRIDE HHHHHHHHCCCHHHH | 45.12 | 15277518 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SNP25_CHICK !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SNP25_CHICK !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SNP25_CHICK !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| KCMA1_CHICK | KCNMA1 | physical | 22174833 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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