SNAB_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SNAB_MOUSE
• UniProt AC: P28663
• Protein Name: Beta-soluble NSF attachment protein
• Gene Name: Napb
• Organism: Mus musculus (Mouse).
• Sequence Length: 298
• Subcellular Localization: Membrane; Peripheral membrane protein.
• Protein Description: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus..
• Protein Sequence: MDNAGKEREAVQLMAEAEKRVKASHSFLRGLFGGNTRIEEACEMYTRAANMFKMAKNWSAAGNAFCQAAKLHMQLQSKHDSATSFVDAGNAYKKADPQEAINCLNAAIDIYTDMGRFTIAAKHHITIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQKAIEIYEQVGANTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYEEMFPAFTDSRECKLLKKLLEAHEEQNSEAYTEAVKEFDSISRLDQWLTTMLLRIKKSIQGDGEGDGDLK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MDNAGKER -------CCCCHHHH	8.94	-
19	Ubiquitination	QLMAEAEKRVKASHS HHHHHHHHHHHHHHH	70.33	-
26	Phosphorylation	KRVKASHSFLRGLFG HHHHHHHHHHHHHHC	24.39	-
56	Ubiquitination	ANMFKMAKNWSAAGN HHHHHHHHCHHHHHH	56.29	-
59	Ubiquitination	FKMAKNWSAAGNAFC HHHHHCHHHHHHHHH	20.03	27667366
66	S-nitrosylation	SAAGNAFCQAAKLHM HHHHHHHHHHHHHHH	2.21	22588120
77	Phosphorylation	KLHMQLQSKHDSATS HHHHHHHCCCCCCHH	40.32	-
92	Phosphorylation	FVDAGNAYKKADPQE HHCCCHHHHCCCHHH	19.61	-
93	Acetylation	VDAGNAYKKADPQEA HCCCHHHHCCCHHHH	38.79	19846971
93	Ubiquitination	VDAGNAYKKADPQEA HCCCHHHHCCCHHHH	38.79	-
94	Acetylation	DAGNAYKKADPQEAI CCCHHHHCCCHHHHH	45.40	19843283
103	S-nitrosylation	DPQEAINCLNAAIDI CHHHHHHHHHHHHHH	2.24	22178444
103	S-nitrosocysteine	DPQEAINCLNAAIDI CHHHHHHHHHHHHHH	2.24	-
109	Ubiquitination	NCLNAAIDIYTDMGR HHHHHHHHHHHHCCC	24.10	27667366
151	Phosphorylation	HYEQSADYYKGEESN HHHHHCCCCCCCCCC	13.54	29899451
152	Phosphorylation	YEQSADYYKGEESNS HHHHCCCCCCCCCCC	17.05	20415495
153	Ubiquitination	EQSADYYKGEESNSS HHHCCCCCCCCCCCH	54.33	27667366
157	Phosphorylation	DYYKGEESNSSANKC CCCCCCCCCCHHHHH	37.40	20415495
159	Phosphorylation	YKGEESNSSANKCLL CCCCCCCCHHHHHHH	39.86	20415495
160	Phosphorylation	KGEESNSSANKCLLK CCCCCCCHHHHHHHH	39.86	20415495
163	Ubiquitination	ESNSSANKCLLKVAA CCCCHHHHHHHHHHH	26.44	-
167	Ubiquitination	SANKCLLKVAAYAAQ HHHHHHHHHHHHHHH	19.51	-
191	Ubiquitination	IYEQVGANTMDNPLL HHHHHCCCCCCCCCH	29.97	27667366
199	Ubiquitination	TMDNPLLKYSAKDYF CCCCCCHHHHHHHHH	44.86	-
200	Phosphorylation	MDNPLLKYSAKDYFF CCCCCHHHHHHHHHH	17.52	25367039
203	Acetylation	PLLKYSAKDYFFKAA CCHHHHHHHHHHHHH	47.20	22826441
203	Ubiquitination	PLLKYSAKDYFFKAA CCHHHHHHHHHHHHH	47.20	27667366
208	Ubiquitination	SAKDYFFKAALCHFI HHHHHHHHHHHHHHH	23.89	-
227	Ubiquitination	NAKLALEKYEEMFPA HHHHHHHHHHHHCHH	59.83	-
246	Ubiquitination	RECKLLKKLLEAHEE HHHHHHHHHHHHHHH	59.27	-
256	Phosphorylation	EAHEEQNSEAYTEAV HHHHHHCHHHHHHHH	24.25	29899451
259	Phosphorylation	EEQNSEAYTEAVKEF HHHCHHHHHHHHHHH	10.89	25521595
264	Ubiquitination	EAYTEAVKEFDSISR HHHHHHHHHHHHHHH	60.76	-
285	Ubiquitination	TMLLRIKKSIQGDGE HHHHHHHHHHCCCCC	50.88	27667366
298	Ubiquitination	GEGDGDLK------- CCCCCCCC-------	64.13	-
298	Acetylation	GEGDGDLK------- CCCCCCCC-------	64.13	19846977

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SNAB_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SNAB_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SNAB_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of SNAB_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.