SNAA_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SNAA_MOUSE
• UniProt AC: Q9DB05
• Protein Name: Alpha-soluble NSF attachment protein
• Gene Name: Napa
• Organism: Mus musculus (Mouse).
• Sequence Length: 295
• Subcellular Localization: Cell membrane ; Peripheral membrane protein .
• Protein Description: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Together with GNA12 promotes CDH5 localization to plasma membrane..
• Protein Sequence: MDNSGKQAEAMALLAEAERKVKNSQSFFSGLFGGSSKIEEACEIYARAANMFKMAKNWSAAGNAFCQAAQLHLQLQSKHDAATCFVDAGNAFKKADPQEAINCLMRAIEIYTDMGRFTIAAKHHISIAEIYETELVDVEKAIAHYEQSADYYKGEESNSSANKCLLKVAGYAAQLEQYQKAIDIYEQVGTSAMDSPLLKYSAKDYFFKAALCHFCIDMLNAKLAVQKYEELFPAFSDSRECKLMKKLLEAHEEQNVDSYTEAVKEYDSISRLDQWLTTMLLRIKKTIQGDEEDLR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MDNSGKQA -------CCCHHHHH	11.26	-
6	Ubiquitination	--MDNSGKQAEAMAL --CCCHHHHHHHHHH	46.27	22790023
22	Ubiquitination	AEAERKVKNSQSFFS HHHHHHHHCCHHHHC	54.65	22790023
24	Phosphorylation	AERKVKNSQSFFSGL HHHHHHCCHHHHCCH	22.83	29899451
26	Phosphorylation	RKVKNSQSFFSGLFG HHHHCCHHHHCCHHC	28.25	22817900
29	Phosphorylation	KNSQSFFSGLFGGSS HCCHHHHCCHHCCCH	32.35	22817900
35	Phosphorylation	FSGLFGGSSKIEEAC HCCHHCCCHHHHHHH	28.92	20415495
36	Phosphorylation	SGLFGGSSKIEEACE CCHHCCCHHHHHHHH	40.71	20415495
42	S-nitrosylation	SSKIEEACEIYARAA CHHHHHHHHHHHHHH	3.55	21278135
42	S-nitrosocysteine	SSKIEEACEIYARAA CHHHHHHHHHHHHHH	3.55	-
93	Acetylation	VDAGNAFKKADPQEA EECCHHHHHCCHHHH	44.64	130581
94	Malonylation	DAGNAFKKADPQEAI ECCHHHHHCCHHHHH	52.12	26320211
94	Acetylation	DAGNAFKKADPQEAI ECCHHHHHCCHHHHH	52.12	130577
151	Phosphorylation	HYEQSADYYKGEESN HHHHHCCCCCCCCCC	13.54	29899451
152	Phosphorylation	YEQSADYYKGEESNS HHHHCCCCCCCCCCC	17.05	20415495
153	Ubiquitination	EQSADYYKGEESNSS HHHCCCCCCCCCCCH	54.33	27667366
157	Phosphorylation	DYYKGEESNSSANKC CCCCCCCCCCHHHHH	37.40	20415495
159	Phosphorylation	YKGEESNSSANKCLL CCCCCCCCHHHHHHH	39.86	20415495
160	Phosphorylation	KGEESNSSANKCLLK CCCCCCCHHHHHHHH	39.86	20415495
163	Ubiquitination	ESNSSANKCLLKVAG CCCCHHHHHHHHHHH	26.44	-
164	Glutathionylation	SNSSANKCLLKVAGY CCCHHHHHHHHHHHH	5.58	24333276
167	Ubiquitination	SANKCLLKVAGYAAQ HHHHHHHHHHHHHHH	19.65	22790023
190	Phosphorylation	DIYEQVGTSAMDSPL HHHHHHCCCCCCCCC	17.92	25293948
191	Phosphorylation	IYEQVGTSAMDSPLL HHHHHCCCCCCCCCH	18.70	25293948
195	Phosphorylation	VGTSAMDSPLLKYSA HCCCCCCCCCHHCCH	12.36	26745281
200	Phosphorylation	MDSPLLKYSAKDYFF CCCCCHHCCHHHHHH	17.52	25367039
203	Ubiquitination	PLLKYSAKDYFFKAA CCHHCCHHHHHHHHH	47.20	22790023
203	Acetylation	PLLKYSAKDYFFKAA CCHHCCHHHHHHHHH	47.20	22647385
227	Ubiquitination	NAKLAVQKYEELFPA HHHHHHHHHHHHHHH	48.29	22790023
285	Ubiquitination	TMLLRIKKTIQGDEE HHHHHHHHHHCCCHH	48.79	22790023

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SNAA_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SNAA_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SNAA_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of SNAA_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.