SMS_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SMS_HUMAN
• UniProt AC: P61278
• Protein Name: Somatostatin
• Gene Name: SST
• Organism: Homo sapiens (Human).
• Sequence Length: 116
• Subcellular Localization: Secreted.
• Protein Description: Somatostatin inhibits the release of somatotropin..
• Protein Sequence: MLSCRLQCALAALSIVLALGCVTGAPSDPRLRQFLQKSLAAAAGKQELAKYFLAELLSEPNQTENDALEPEDLSQAAEQDEMRLELQRSANSNPAMAPRERKAGCKNFFWKTFTSC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MLSCRLQCAL -----CCHHHHHHHH	8.90	22210691
14	Phosphorylation	QCALAALSIVLALGC HHHHHHHHHHHHHHH	13.11	22210691
23	Phosphorylation	VLALGCVTGAPSDPR HHHHHHHHCCCCCHH	31.53	22210691
27	Phosphorylation	GCVTGAPSDPRLRQF HHHHCCCCCHHHHHH	60.76	22210691
43	Amidation	QKSLAAAAGKQELAK HHHHHHHHCHHHHHH	22.46	-
58	Phosphorylation	YFLAELLSEPNQTEN HHHHHHHCCCCCCCC	64.73	26657352
74	Phosphorylation	ALEPEDLSQAAEQDE CCCHHHHHHHHHHHH	30.05	26657352

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SMS_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SMS_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SMS_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of SMS_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.