SMIM8_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SMIM8_HUMAN
• UniProt AC: Q96KF7
• Protein Name: Small integral membrane protein 8
• Gene Name: SMIM8
• Organism: Homo sapiens (Human).
• Sequence Length: 97
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MSSAPEPPTFKKEPPKEKEFQSPGLRGVRTTTLFRAVNPELFIKPNKPVMAFGLVTLSLCVAYIGYLHAIQENKKDLYEAIDSEGHSYMRRKTSKWD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSSAPEPPT ------CCCCCCCCC		-
3	Phosphorylation	-----MSSAPEPPTF -----CCCCCCCCCC		-
9	Phosphorylation	SSAPEPPTFKKEPPK CCCCCCCCCCCCCCC		26074081
26	Methylation	EFQSPGLRGVRTTTL CCCCCCCCCCCHHHH		115917281
30	Phosphorylation	PGLRGVRTTTLFRAV CCCCCCCHHHHHHCC		23186163
31	Phosphorylation	GLRGVRTTTLFRAVN CCCCCCHHHHHHCCC		23186163
44	Acetylation	VNPELFIKPNKPVMA CCHHHCCCCCCCCHH		19608861
78	Phosphorylation	QENKKDLYEAIDSEG HHCCHHHHHHHHCCC		-
83	Phosphorylation	DLYEAIDSEGHSYMR HHHHHHHCCCHHHHC		24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SMIM8_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SMIM8_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SMIM8_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of SMIM8_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.