| UniProt ID | SMCA1_MOUSE | |
|---|---|---|
| UniProt AC | Q6PGB8 | |
| Protein Name | Probable global transcription activator SNF2L1 | |
| Gene Name | Smarca1 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 1046 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Energy-transducing component of the NURF (nucleosome-remodeling factor) and CERF (CECR2-containing-remodeling factor) complexes, which facilitate the perturbation of chromatin structure in an ATP-dependent manner.. | |
| Protein Sequence | MEPDTATEAATVAVSDARATVVVVEDEQPGPSTFKEEGAAAAATEGTTATEKGEKKEKITSPFQLKLAAKASKSEKEMDPEYEEKMVNMPLKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSPLNMKLARPRVKKDDKQSLISVGDYRHRRTEQEEDEELLSESRKTSNVCVRFEVSPSYVKGGPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDVRAAFIRDEMMPGEWDVCVTSYEMVIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEHIVGNSGKMVALDKLLARIKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYSRLDGQTPHEEREEAIDAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKLAKEEMLQMIRHGATHVFACKESELTDEDIVTILERGEKKTAEMNERMQKMGESSLRNFRMDLEQSLYKFEGEDYREKQKLGTVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPEIPNPAIAQREEQKKIDGAEPLTPQETEEKDKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSPEEVMEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGKNYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLISLIEKENMEIEERERAEKKKRATKTPMVKFSAFS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 61 | Phosphorylation | EKKEKITSPFQLKLA CCHHCCCCHHHHHHH | 27.47 | 26643407 | |
| 72 | Phosphorylation | LKLAAKASKSEKEMD HHHHHHHCCCCCCCC | 35.69 | 23737553 | |
| 74 | Phosphorylation | LAAKASKSEKEMDPE HHHHHCCCCCCCCHH | 51.94 | 23737553 | |
| 120 | Phosphorylation | IQPSAQKSPTSPLNM HCCCCCCCCCCCCCH | 22.72 | 26643407 | |
| 122 | Phosphorylation | PSAQKSPTSPLNMKL CCCCCCCCCCCCHHC | 50.49 | 26643407 | |
| 123 | Phosphorylation | SAQKSPTSPLNMKLA CCCCCCCCCCCHHCC | 30.67 | 26643407 | |
| 153 | Phosphorylation | GDYRHRRTEQEEDEE HCCCCCCCCHHHHHH | 41.81 | 29514104 | |
| 444 | Phosphorylation | KDIDVLNSSGKMDKM HHHHHHCCCCCCCHH | 35.99 | 27149854 | |
| 701 | Acetylation | EMNERMQKMGESSLR HHHHHHHHHHHHHHH | 39.26 | 7720475 | |
| 762 | Phosphorylation | FREALRVSEPKIPKA HHHHHHCCCCCCCCC | 41.57 | 28066266 | |
| 946 | Phosphorylation | FHQLRIQYGTSKGKN HHHHHHCCCCCCCCC | 21.72 | - | |
| 1051 (in isoform 2) | Phosphorylation | - | 25338131 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SMCA1_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SMCA1_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SMCA1_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of SMCA1_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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