SLMAP_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SLMAP_MOUSE
• UniProt AC: Q3URD3
• Protein Name: Sarcolemmal membrane-associated protein
• Gene Name: Slmap
• Organism: Mus musculus (Mouse).
• Sequence Length: 845
• Subcellular Localization: Cell membrane, sarcolemma; Single-pass type IV membrane protein. Cytoplasm, myofibril, sarcomere, M line. Cytoplasm, myofibril, sarcomere, Z line. Membrane-associated. Distributed in the transverse tubules and near the junctional sarcoplasmic reticul
• Protein Description: May play a role during myoblast fusion..
• Protein Sequence: MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWFDHKTSKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKVTHGCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKELIALQEDKHSYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQTKIDEMEEKEQELQAKIEALQADNDFTNERLTALQVRLEHLQEKTLKECSSLGIQVDDFLPKINGSTEKEHLLSKSGGDCTFIHQFLECQKKLMVQGHLTKVVEESKLSKENQAKAKESDLSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGTQSETEAKQDIQHLRKELVEAQELARTSKQKCFELQALLEEERKAYRNQVEESAKQIQVLQVQLQKLHMDMENLQEEKDTEISSTRDKLLSAQDEILLLRQAAAEAVSERDTDFVSLQEELKKVRAELEGWRKAASEYENEIRSLQSSFQLRCQQCEDQQREEATRLQGELEKLKKEWDVLETECHSLKKENVLLSSELQRQEKELHNSQKQSFELTSDLSILQMTRKELEKQVGSLKEQHLRDAADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKDNLKLLREKGNNKPWPWMPMLAALVAVTAMVLYVPGLARASP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
33	Phosphorylation	EPIKIGRSVARCRPA CCCCCCCCCCCCCCC	18.21	-
89	Phosphorylation	SQRLSRGSEESPPCE CEECCCCCCCCCCCE	36.76	22807455
139	Phosphorylation	GMEARLRSDVIHAPL CHHHHCCCCCCCCCC	40.60	25159016
148	Phosphorylation	VIHAPLPSPVDKVAA CCCCCCCCCCCHHHC	45.28	25521595
232	Phosphorylation	QACSKNQTEDSLRKE HHHCCCCCHHHHHHH	51.67	28285833
235	Phosphorylation	SKNQTEDSLRKELIA CCCCCHHHHHHHHHH	24.68	26824392
273	Phosphorylation	IEVVRKLSEVERSLS HHHHHHHHHHHHHHC	42.50	29472430
278	Phosphorylation	KLSEVERSLSNTEDE HHHHHHHHHCCCHHH	23.73	30635358
280	Phosphorylation	SEVERSLSNTEDECT HHHHHHHCCCHHHHH	42.84	30635358
282	Phosphorylation	VERSLSNTEDECTHL HHHHHCCCHHHHHHH	41.24	25521595
307	Phosphorylation	LRELANKYNGAVNEI HHHHHHHHCCHHHHH	20.73	25177544
419	Phosphorylation	KEHLLSKSGGDCTFI HHHHHHCCCCCCCHH	44.63	-
462	Phosphorylation	NQAKAKESDLSDTLS HHHHHHHCCCCCCCC	43.05	25619855
465	Phosphorylation	KAKESDLSDTLSPSK HHHHCCCCCCCCCCC	33.27	25619855
467	Phosphorylation	KESDLSDTLSPSKEK HHCCCCCCCCCCCCC	26.26	25619855
469	Phosphorylation	SDLSDTLSPSKEKSS CCCCCCCCCCCCCCC	29.26	25521595
471	Phosphorylation	LSDTLSPSKEKSSDD CCCCCCCCCCCCCCC	50.50	25619855
475	Phosphorylation	LSPSKEKSSDDTTDA CCCCCCCCCCCCCHH	39.84	25521595
476	Phosphorylation	SPSKEKSSDDTTDAQ CCCCCCCCCCCCHHH	51.04	29899451
480	Phosphorylation	EKSSDDTTDAQMDEQ CCCCCCCCHHHHCHH	36.01	25521595
500	Acetylation	LAKVSLLKDDLQGTQ HHHHHHHHHHHCCCC	55.26	19855893
506	Phosphorylation	LKDDLQGTQSETEAK HHHHHCCCCCHHHHH	18.89	29899451
510	Phosphorylation	LQGTQSETEAKQDIQ HCCCCCHHHHHHHHH	46.63	29899451
759	Ubiquitination	DLKTLLSKAENQAKD HHHHHHHHHHHHHHH	60.74	22790023

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SLMAP_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SLMAP_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SLMAP_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of SLMAP_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.