dbPTM

SLIP1_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SLIP1_DROME
UniProt AC	Q8MR31
Protein Name	Slo-interacting protein 1
Gene Name	Slip1
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	767
Subcellular Localization
Protein Description	May selectively reduce calcium-activated potassium channel (Slo) currents by reducing the number of Slo channels in the plasma membrane..
Protein Sequence	MSIADVEYEYVVLKINGYDISHLSRYEAVQKFLQSKETLVVEIRRQKHNALDLELKHGSNAKISKVDNPGELSVLTDKSAEGTITAASASQQINCPSSTSLKEIETKTPVVLTLRARSHEDRLGSLQAASKETQTQSVVGTDVLKDNDLVNTITDNFIEHEHHLFEQCLEPEIDIEEVTLVKGVEQSSSNQIGLIVTSSGIQQSSTDTNKGDILGNVLEHSEDVFISGVQPESIAYRDGRLRQGDQILRINGLDVKNQEELETQIARSSTSVTLLVSRILYPEDDDDEDIHFEYANTFLPDDYTNVVDKLDKVLLTHVKSLEELSNKSAMQSDECYHIPEKNSSDSNVKISSLAKNIIEQSTKSCSKIKLRPNANLDYKKKFNLPLSQEEVHLQYEYDESEHIYETIPEDSESEPVYCSPYQRSNDKTSIGCSSPIASRPAESLERTMQQQTQRVAQWLGLKPQYQKTRQTLVGRPPPLKLVQQPTCSRVFTLRSTLTNTSASSSSGVAYSSYGQNNVVTGNAAAPGEEVDNSSSAYNTGDSNNSASPHQNTTNPDEAIATGRKLDSTVIDSPNDHLDATGVSTMLLLPFGKSGRIGLCSSNLPTAYVSERYTNVGSENEIHPLKSDIEILRVKPTDDSYSHCPQFNAPNLSSYHFVSSQEVANRCHISTSLQKNATLLNGESAEEIPMVWKVKRRPDGTRYIVKRPVRNRPQVALRKNMRYNEVTTTEDDTISEVKIGRYWTKEERKRHIERAREKRHHQTQQQQQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
320	Phosphorylation	VLLTHVKSLEELSNK HHHHHHHCHHHHCCC	39.67	19429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SLIP1_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SLIP1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SLIP1_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
ECO_DROME	eco	physical	14605208
SLO_DROME	slo	physical	9502797

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SLIP1_DROME

Related Literatures of Post-Translational Modification