SKDA1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SKDA1_HUMAN
• UniProt AC: Q1XH10
• Protein Name: SKI/DACH domain-containing protein 1
• Gene Name: SKIDA1
• Organism: Homo sapiens (Human).
• Sequence Length: 908
• Protein Sequence: MGDLKSGFEEVDGVRLGYLIIKGKQMFALSQVFTDLLKNIPRTTVHKRMDHLKVKKHHCDLEELRKLKAINSIAFHAAKCTLISREDVEALYTSCKTERVLKTKRRRVGRALATKAPPPERAAAASPRPGFWKDKHQLWRGLSGAARPLPISAQSQRPGAAAARPAAHLPQIFSKYPGSHYPEIVRSPCKPPLNYETAPLQGNYVAFPSDPAYFRSLLCSKHPAAAAAAAAAAAAAAAAAAAAAYYQVSAAGPQPKAAAGAGGPGSLSYRCKRKRGGAKDCLLAPHAGARRLLLLPRSYKAKAAAAAAAAAAAAAAAAGATCLERFHLVNGFCPPPHHHHHHHHHHHHHHHRAQPPQQSHHPPHHHRPQPHLGSFPESCSSDSESSSYSDHAANDSDFGSSLSSSSNSVSSEEEEEEGEEEEEEEEEEGGSGASDSSEVSSEEEDSSTESDSSSGSSQVSVQSIRFRRTSFCKPPSVQAQANFLYHLASAAAATKPAAFEDAGRLPDLKSSVKAESPAEWNLQSWAPKASPVYCPASLGSCFAEIRNDRVSEITFPHSEISNAVKRTDLTINCLAEGASSPSPKTNNAFPQQRILREARKCLQTTPTTHCADNNTIAARFLNNDSSGAEANSEKYSKILHCPEFATDLPSSQTDPEVNAAGAAATKAENPCTDTGDKTLPFLHNIKIKVEDSSANEEYEPHLFTNKLKCECNDTKGEFYSVTESKEEDALLTTAKEGFACPEKETPSLNPLAQSQGLSCTLGSPKPEDGEYKFGARVRKNYRTLVLGKRPVLQTPPVKPNLKSARSPRPTGKTETNEGTLDDFTVINRRKKVASNVASAVKRPFHFMANFPCPPSLIIGRDGDLWPAYSLNTTKDSQTPHKAHPIWKWQLGGSAIPLPPSHKFRKFNS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
34	Phosphorylation	FALSQVFTDLLKNIP HHHHHHHHHHHHCCC		-
72	Phosphorylation	RKLKAINSIAFHAAK HHHHHHHHHHHHHHH		24719451
81	Phosphorylation	AFHAAKCTLISREDV HHHHHHCEEEEHHHH		24719451
93	Phosphorylation	EDVEALYTSCKTERV HHHHHHHHHHCHHHH		24719451
143	Phosphorylation	HQLWRGLSGAARPLP HHHHHHHCCCCCCCC		27174698
152	Phosphorylation	AARPLPISAQSQRPG CCCCCCCCCCCCCCC		27174698
155	Phosphorylation	PLPISAQSQRPGAAA CCCCCCCCCCCCHHH		27174698
174	Phosphorylation	AHLPQIFSKYPGSHY HHHHHHHHCCCCCCC		24719451
216	Phosphorylation	SDPAYFRSLLCSKHP CCHHHHHHHHHCCCH		23898821
240	Phosphorylation	AAAAAAAAAAAAYYQ HHHHHHHHHHHHHHH		23898821
449	Phosphorylation	EEEDSSTESDSSSGS CCCCCCCCCCCCCCC		30631047
459	Phosphorylation	SSSGSSQVSVQSIRF CCCCCCCEEEEEEEE		30631047
498	Phosphorylation	AAATKPAAFEDAGRL HHHCCCHHHHCCCCC		22496350
499	Phosphorylation	AATKPAAFEDAGRLP HHCCCHHHHCCCCCC		22496350
501	Phosphorylation	TKPAAFEDAGRLPDL CCCHHHHCCCCCCCH		22496350
504	Phosphorylation	AAFEDAGRLPDLKSS HHHHCCCCCCCHHHH		-
579	Phosphorylation	NCLAEGASSPSPKTN HHHHCCCCCCCCCCC		-
580	Phosphorylation	CLAEGASSPSPKTNN HHHCCCCCCCCCCCC		-
582	Phosphorylation	AEGASSPSPKTNNAF HCCCCCCCCCCCCCC		-
585	Phosphorylation	ASSPSPKTNNAFPQQ CCCCCCCCCCCCHHH		-
682	Phosphorylation	GDKTLPFLHNIKIKV CCCCCCCEEEEEEEE		-
688	Sumoylation	FLHNIKIKVEDSSAN CEEEEEEEEECCCCC		28112733
721	Methylation	TKGEFYSVTESKEED CCCCEEEECCCHHHH		-
763	Phosphorylation	GLSCTLGSPKPEDGE CCCEECCCCCCCCCC		-
802	Methylation	PPVKPNLKSARSPRP CCCCCCCCCCCCCCC		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SKDA1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SKDA1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SKDA1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of SKDA1_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.