SIM14_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SIM14_RAT
• UniProt AC: Q498C7
• Protein Name: Small integral membrane protein 14
• Gene Name: Smim14
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 99
• Subcellular Localization: Endoplasmic reticulum membrane; Single-pass membrane protein.
• Protein Sequence: MAEGGFDPCECICSHEHAMRRLINLLRQSQSYCTDTECLRELPGPSGDSGISITVILMAWMVIAVLLFLLRPPNLRGSSLPGKPSSPHSGQDPPAPPVD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
78	Phosphorylation	RPPNLRGSSLPGKPS CCCCCCCCCCCCCCC		25575281
79	Phosphorylation	PPNLRGSSLPGKPSS CCCCCCCCCCCCCCC		25575281
83	Ubiquitination	RGSSLPGKPSSPHSG CCCCCCCCCCCCCCC		-
85	Phosphorylation	SSLPGKPSSPHSGQD CCCCCCCCCCCCCCC		25575281
86	Phosphorylation	SLPGKPSSPHSGQDP CCCCCCCCCCCCCCC		25575281
89	Phosphorylation	GKPSSPHSGQDPPAP CCCCCCCCCCCCCCC		25575281

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SIM14_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SIM14_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SIM14_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of SIM14_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.