| UniProt ID | SIA8F_MOUSE | |
|---|---|---|
| UniProt AC | Q8K4T1 | |
| Protein Name | Alpha-2,8-sialyltransferase 8F | |
| Gene Name | St8sia6 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 398 | |
| Subcellular Localization |
Golgi apparatus membrane Single-pass type II membrane protein . |
|
| Protein Description | Prefers O-glycans to N-glycans or glycolipids as acceptor substrates. The minimal acceptor substrate is the NeuAc-alpha-2,3(6)-Gal sequence at the non-reducing end of their carbohydrate groups.. | |
| Protein Sequence | MRSGGTLFALIGSLMLLLLLRMLWCPADAPARSRLLMEGSREDTSGTSAALKTLWSPTTPVPRTRNSTYLDEKTTQITEKCKDLQYSLNSLSNKTRRYSEDDYLQTITNIQRCPWNRQAEEYDNFRAKLASCCDAIQDFVVSQNNTPVGTNMSYEVESKKHIPIRENIFHMFPVSQPFVDYPYNQCAVVGNGGILNKSLCGAEIDKSDFVFRCNLPPITGSASKDVGSKTNLVTVNPSIITLKYQNLKEKKAQFLEDISTYGDAFLLLPAFSYRANTGISFKVYQTLKESKMRQKVLFFHPRYLRHLALFWRTKGVTAYRLSTGLMIASVAVELCENVKLYGFWPFSKTIEDTPLSHHYYDNMLPKHGFHQMPKEYSQMLQLHMRGILKLQFSKCETA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 66 | N-linked_Glycosylation | TPVPRTRNSTYLDEK CCCCCCCCCCCCCHH | 37.78 | - | |
| 93 | N-linked_Glycosylation | YSLNSLSNKTRRYSE HHHHHCCCCCCCCCH | 55.82 | - | |
| 151 | N-linked_Glycosylation | NNTPVGTNMSYEVES CCCCCCCCEEEEECC | 16.09 | - | |
| 196 | N-linked_Glycosylation | VGNGGILNKSLCGAE EECCCCCCHHHCCCE | 29.92 | - | |
| 376 | Phosphorylation | FHQMPKEYSQMLQLH CCCCCHHHHHHHHHH | 15.44 | 26745281 | |
| 377 | Phosphorylation | HQMPKEYSQMLQLHM CCCCHHHHHHHHHHH | 15.37 | 29899451 | |
| 393 | Phosphorylation | GILKLQFSKCETA-- HHHHEEECCCCCC-- | 24.36 | 29899451 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SIA8F_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SIA8F_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SIA8F_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of SIA8F_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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