| UniProt ID | SGCE_MOUSE | |
|---|---|---|
| UniProt AC | O70258 | |
| Protein Name | Epsilon-sarcoglycan | |
| Gene Name | Sgce | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 437 | |
| Subcellular Localization |
Cell membrane, sarcolemma Single-pass membrane protein . Golgi apparatus . Cell projection, dendrite . Cytoplasm, cytoskeleton. |
|
| Protein Description | Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.. | |
| Protein Sequence | MLLFWWWELGDPCAWTGKGRGTLKMSPATTGTFLLTVYTLFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEVSNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTIIEITAYNRRTFETARHNLIINIMSAEEFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDMKEGVYVMVGADVAFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTHFHIDWCKISLVDKTKQVSTYQEVVRGEGILPDGGEYKPPSDSLKSRDYYTDFLVTLAVPSAVALVLFLILAYIMCCRREGVEKRDMQTPDIQLVHHSSIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEVIPPTHTDNYDSTNMPLMQAQQNLPHQTQIPQPQTTGKWYP | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 74 (in isoform 2) | Phosphorylation | - | 24.91 | 28285833 | |
| 75 (in isoform 2) | Phosphorylation | - | 41.98 | 28285833 | |
| 200 | N-linked_Glycosylation | PERLNAINITSALDR HHHHCCCCCCCCCCC | 29.13 | - | |
| 237 | Methylation | VAFSSCLREVENPQN CHHHHHHHHCCCHHH | 50.68 | 16188853 | |
| 280 | Acetylation | ISLVDKTKQVSTYQE EEEECCCCCCCCHHH | 55.21 | 22826441 | |
| 353 | Phosphorylation | VEKRDMQTPDIQLVH CCCCCCCCCCEEEEC | 19.11 | 26370283 | |
| 362 | Phosphorylation | DIQLVHHSSIQKSTK CEEEECHHHHHHHHH | 17.79 | 27742792 | |
| 363 | Phosphorylation | IQLVHHSSIQKSTKE EEEECHHHHHHHHHH | 25.36 | 28978645 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SGCE_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SGCE_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SGCE_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of SGCE_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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