dbPTM

SFXN1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SFXN1_MOUSE
UniProt AC	Q99JR1
Protein Name	Sideroflexin-1
Gene Name	Sfxn1
Organism	Mus musculus (Mouse).
Sequence Length	322
Subcellular Localization	Mitochondrion membrane Multi-pass membrane protein.
Protein Description	Might be involved in the transport of a component required for iron utilization into or out of the mitochondria..
Protein Sequence	MSGEVPPNINIKEPRWDQSTFIGRASHFFTVTDPRNILLTNEQLENARKVVHDYRQGIVPAGLTENELWRAKYAYDSAFHPDTGEKMTLIGRMSAQVPMNMTITGCMMTFYRTTPAVLFWQWINQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKRVSPLIGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENGTRLGESTNAAKQAITQVVISRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPIQVTLVGFCLVFATPLCCALFPQKSSMSVTSLEDELQASIQRTHPEIRRVYFNKGL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSGEVPPNI ------CCCCCCCCC	43.60	-
72	Acetylation	ENELWRAKYAYDSAF HHHHHHHHHCCCCCC	23.11	23954790
173	Phosphorylation	NALTKRVSPLIGRFV HHHHHCHHHHHCCHH	20.30	19367708
291	Phosphorylation	CALFPQKSSMSVTSL HHHCCCCCCCCCCCH	26.48	23140645
292	Phosphorylation	ALFPQKSSMSVTSLE HHCCCCCCCCCCCHH	23.32	23140645
294	Phosphorylation	FPQKSSMSVTSLEDE CCCCCCCCCCCHHHH	24.96	23140645
296	Phosphorylation	QKSSMSVTSLEDELQ CCCCCCCCCHHHHHH	21.93	23140645
297	Phosphorylation	KSSMSVTSLEDELQA CCCCCCCCHHHHHHH	27.83	23140645
317	Phosphorylation	HPEIRRVYFNKGL-- CHHHHHHHHCCCC--	10.30	29899451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SFXN1_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SFXN1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SFXN1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of SFXN1_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SFXN1_MOUSE

Related Literatures of Post-Translational Modification