SETBP_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SETBP_MOUSE
• UniProt AC: Q9Z180
• Protein Name: SET-binding protein
• Gene Name: Setbp1
• Organism: Mus musculus (Mouse).
• Sequence Length: 1582
• Subcellular Localization: Nucleus.
• Protein Sequence: MEPREMLSSCRQRGSESEFLQGSSSRSPPAPGCSGEPLKGISVGGERMEPEEEDELGSGRDVDCNSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRTGKNSKATKEDERNHSKKKLLTAGDPTASDLKAFQTQAYERPQKHSTLQYDPGHSQGFTSDTLKPKHQQKSSSQSHMEWSSNSDSGPATQNCFISPEAGRDTASTSKVPALEPVASFAKAQSKKGSTGGAWSQLSSSSKDLLLGSVVPSPSSHNSPATPSSSAECNGLQPLGDQDGGSTKDLPEPPTLSSKKKSSKKDMISQTLPNSDLDWVKSAQKAFETTEGKREAYSADSAQEASPARQSISSVSNPENDSSHVRITIPIKTPSLDPSNHKRKKRQSIKAVVEKIVPEKALASGISMSSEVVNRILSNSEGSKKDPRVPKLGKMIENETPSVGLETGGNAEKIVPGGASKQRKPPMVMTSPTRTEHAPSGKLSEIQHPKFAAKRRCSKAKPPAMLREAVLATAEKLMVEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVETIHEGTSTSPVSPISREFPGTKKRKRRRNLAKLAQLVPGEDKPMSEMKFHKKVGKLGVLDKKTIKTINKMKTLKRKNILNQILSCSSSVALKAKAPPETSPGAASIESKLGKQINVSKRGTIYIGKKRGRKPRTELPPPSEEPKTAIKHPRPVSSQPDVPAVPSSFQSPVASSPAAMHPLSTQLGGSNGNLSPASTETNFSELKTMPNLQPISALPTKTQKGIHGGTWKLSPPRLMANSPSHLCEIGSLKEITLSPVSESHSEETIPSDSGIGTDNNSTSDQAEKSSESRRRYSFDFCSLDNPEAIPSDTSTKNRHGHRQKHLIVDTFLAHESLKKPKHKRKRKSLQNRDDLQFLAELEELITKFQVFRISHRGYTFYHENPYPSIFRINFDQYYPVPYIQYDPLLYLRRTSDLKSKKKRGRPAKTNDTMTKVPFLQGFSYPIPSGSYYAPYGMPYTSMPMMNLGYYGQYPAPLYLSHTLGAASPFMRPTVPPPQFHASSHVKISGATKHKAKHGVHLQGTVGMGLGDIQPSLNPPKVGGATLSSSRLHKRKHKHKRKHKEDRILGTHDNLSGLFAGKATGFSSHLLSERLSGSDKELPLVSEKSKHKERQKHQHGEASHKVSKNNFEVDTLSTLSLSDAQHWTQAKDKGDLSSEPVESCAKRYSGSGGDSTRSEGLDVFSEMNPSSDKWDSDMGGSKRRSFEGFGTYREKDIQAFKMNRKERGSYESSMSPGMPSPHLKVDQTAAHSKSEGSISAMMARKKPTAVDSVAIPSAPVLSLLAASAATSDAASSSLKKRFKRREIEAIQCEVRKMCHYTKLLSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRGRPRKQPSQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLALEPASGQDAVMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPPPPPPLPKTARGGKRKHRPQPPAQPAQPTPQPLPQEEEVKAKRPRKSRASESDVLP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
15	Phosphorylation	SSCRQRGSESEFLQG HHHHHHCCHHHHHCC	39.89	25338131
350	Phosphorylation	SDLDWVKSAQKAFET CCHHHHHHHHHHHHC	26.72	-
374	Phosphorylation	ADSAQEASPARQSIS CCCHHHCCCCHHHHH	20.52	26824392
508	Phosphorylation	TRTEHAPSGKLSEIQ CCCCCCCCCCHHHCC	49.71	25338131
512	Phosphorylation	HAPSGKLSEIQHPKF CCCCCCHHHCCCHHH	35.82	25338131
541	Phosphorylation	LREAVLATAEKLMVE HHHHHHHHHHHHCCC	31.05	-
599	Phosphorylation	IHEGTSTSPVSPISR ECCCCCCCCCCCCCC	24.07	25338131
602	Phosphorylation	GTSTSPVSPISREFP CCCCCCCCCCCCCCC	21.65	26824392
662	Phosphorylation	KTINKMKTLKRKNIL HHHHHHHHHHHHHHH	33.73	29895711
674	Phosphorylation	NILNQILSCSSSVAL HHHHHHHHCCCHHHH	17.37	29895711
676	Phosphorylation	LNQILSCSSSVALKA HHHHHHCCCHHHHHC	23.44	21454597
677	Phosphorylation	NQILSCSSSVALKAK HHHHHCCCHHHHHCC	32.91	21454597
678	Phosphorylation	QILSCSSSVALKAKA HHHHCCCHHHHHCCC	8.63	29895711
707	Phosphorylation	LGKQINVSKRGTIYI HCCEEEECCCCEEEE	16.49	28059163
808	Acetylation	PISALPTKTQKGIHG CCCCCCCCCCCCCCC	47.20	23806337
821	Phosphorylation	HGGTWKLSPPRLMAN CCCCCCCCCCHHHCC	29.18	26824392
829	Phosphorylation	PPRLMANSPSHLCEI CCHHHCCCHHHEEEE	20.45	26824392
831	Phosphorylation	RLMANSPSHLCEIGS HHHCCCHHHEEEECC	28.98	25168779
845	Phosphorylation	SLKEITLSPVSESHS CCCEEEECCCCCCCC	18.01	25338131
1184	Phosphorylation	LSERLSGSDKELPLV HHHHHCCCCCCCCCC	41.98	29514104
1249	Phosphorylation	LSSEPVESCAKRYSG CCCCCHHHHHHHHCC	21.43	28285833
1291	Phosphorylation	MGGSKRRSFEGFGTY CCCCCCCCCCCCCCC	31.51	25338131
1315	Phosphorylation	MNRKERGSYESSMSP CCHHHCCCCCCCCCC	31.76	29899451
1316	Phosphorylation	NRKERGSYESSMSPG CHHHCCCCCCCCCCC	23.74	29899451
1358	Phosphorylation	KKPTAVDSVAIPSAP CCCCCCCCCCCCCHH	13.57	25777480
1363	Phosphorylation	VDSVAIPSAPVLSLL CCCCCCCCHHHHHHH	38.81	29895711
1368	Phosphorylation	IPSAPVLSLLAASAA CCCHHHHHHHHHHHC	22.90	29895711
1373	Phosphorylation	VLSLLAASAATSDAA HHHHHHHHHCCCHHH	16.90	25777480
1377	Phosphorylation	LAASAATSDAASSSL HHHHHCCCHHHHHHH	22.11	29895711
1382	Phosphorylation	ATSDAASSSLKKRFK CCCHHHHHHHHHHHH	34.66	25777480
1383	Phosphorylation	TSDAASSSLKKRFKR CCHHHHHHHHHHHHH	41.53	25777480
1451	Phosphorylation	GRPRKQPSQFDEDSR CCCCCCCCCCCCCCH	40.77	28285833
1473	Acetylation	KCIDLPSKRGQKPSL HHHCCCCCCCCCCCC	59.62	7823435
1576	Phosphorylation	RPRKSRASESDVLP- CCCCCCCCCCCCCC-	36.20	25338131

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SETBP_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SETBP_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SETBP_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of SETBP_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.