| UniProt ID | SERPH_RAT | |
|---|---|---|
| UniProt AC | P29457 | |
| Protein Name | Serpin H1 | |
| Gene Name | Serpinh1 | |
| Organism | Rattus norvegicus (Rat). | |
| Sequence Length | 417 | |
| Subcellular Localization | Endoplasmic reticulum lumen. | |
| Protein Description | Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.. | |
| Protein Sequence | MRSLLLGTLCLLAVALAAEVKKPVEAAAPGTAEKLSSKATTLAERSTGLAFSLYQAMAKDQAVENILLSPLVVASSLGLVSLGGKATTASQAKAVLSAEKLRDEEVHTGLGELVRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWASQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVTMMHRTGLYNYYDDEKEKLQLVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKTWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFEWDTEGNPFDQDIYGREELRSPKLFYADHPFIFLVRDNQSGSLLFIGRLVRPKGDKMRDEL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 93 | Succinylation | ATTASQAKAVLSAEK CCHHHHHHHHHHHHH | 31.24 | - | |
| 93 | Succinylation | ATTASQAKAVLSAEK CCHHHHHHHHHHHHH | 31.24 | - | |
| 119 | N-linked_Glycosylation | ELVRSLSNSTARNVT HHHHHHCCCCCCCCC | 48.99 | - | |
| 124 | N-linked_Glycosylation | LSNSTARNVTWKLGS HCCCCCCCCCEEECC | 32.86 | - | |
| 137 | Phosphorylation | GSRLYGPSSVSFADD CCCCCCCCCCHHHHH | 38.72 | 23984901 | |
| 138 | Phosphorylation | SRLYGPSSVSFADDF CCCCCCCCCHHHHHH | 25.55 | 23984901 | |
| 140 | Phosphorylation | LYGPSSVSFADDFVR CCCCCCCHHHHHHHH | 19.37 | 23984901 | |
| 171 | Phosphorylation | DKRSALQSINEWASQ HHHHHHHHHHHHHHH | 28.38 | 27097102 | |
| 177 | Phosphorylation | QSINEWASQTTDGKL HHHHHHHHHCCCCCC | 29.18 | 27097102 | |
| 179 | Phosphorylation | INEWASQTTDGKLPE HHHHHHHCCCCCCCC | 25.10 | 27097102 | |
| 180 | Phosphorylation | NEWASQTTDGKLPEV HHHHHHCCCCCCCCC | 34.81 | 27097102 | |
| 206 | Acetylation | LVNAMFFKPHWDEKF EEEEEEECCCCCHHH | 25.38 | - | |
| 216 | Acetylation | WDEKFHHKMVDNRGF CCHHHHHHEECCCCE | 31.86 | 22902405 | |
| 286 | Acetylation | RLEKLLTKEQLKTWM HHHHHCCHHHHHHHH | 43.35 | 22902405 | |
| 290 | Acetylation | LLTKEQLKTWMGKMQ HCCHHHHHHHHHHHH | 39.57 | 22902405 | |
| 295 | Succinylation | QLKTWMGKMQKKAVA HHHHHHHHHHHHHHE | 23.27 | - | |
| 295 | Succinylation | QLKTWMGKMQKKAVA HHHHHHHHHHHHHHE | 23.27 | - | |
| 318 | Acetylation | EVTHDLQKHLAGLGL EHHHHHHHHHCCCCH | 48.13 | 22902405 | |
| 394 | N-linked_Glycosylation | FIFLVRDNQSGSLLF EEEEEECCCCCCEEE | 27.61 | - | |
| 412 | Acetylation | LVRPKGDKMRDEL-- EECCCCHHHCCCC-- | 44.49 | 22902405 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SERPH_RAT !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SERPH_RAT !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SERPH_RAT !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of SERPH_RAT !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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