dbPTM

SERPH_CHICK - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SERPH_CHICK
UniProt AC	P13731
Protein Name	Serpin H1
Gene Name	SERPINH1
Organism	Gallus gallus (Chicken).
Sequence Length	405
Subcellular Localization	Endoplasmic reticulum lumen.
Protein Description	Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen..
Protein Sequence	MQIFLVLALCGLAAAVPSEDRKLSDKATTLADRSTTLAFNLYHAMAKDKNMENILLSPVVVASSLGLVSLGGKATTASQAKAVLSADKLNDDYVHSGLSELLNEVSNSTARNVTWKIGNRLYGPASINFADDFVKNSKKHYNYEHSKINFRDKRSALKSINEWAAQTTDGKLPEVTKDVEKTDGALIVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVPMMHRTGLYNYYDDEAEKLQVVEMPLAHKLSSMIFIMPNHVEPLERVEKLLNREQLKTWASKMKKRSVAISLPKVVLEVSHDLQKHLADLGLTEAIDKTKADLSKISGKKDLYLSNVFHAAALEWDTDGNPYDADIYGREEMRNPKLFYADHPFIFMIKDSKTNSILFIGRLVRPKGDKMRDEL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
107	N-linked_Glycosylation	ELLNEVSNSTARNVT HHHHHHCCCCCCCCC	48.86	-
112	N-linked_Glycosylation	VSNSTARNVTWKIGN HCCCCCCCCCEEECC	32.86	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SERPH_CHICK !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SERPH_CHICK !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SERPH_CHICK !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of SERPH_CHICK !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SERPH_CHICK

Related Literatures of Post-Translational Modification