SERP2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SERP2_HUMAN
• UniProt AC: Q8N6R1
• Protein Name: Stress-associated endoplasmic reticulum protein 2
• Gene Name: SERP2
• Organism: Homo sapiens (Human).
• Sequence Length: 65
• Subcellular Localization: Membrane; Single-pass type IV membrane protein. Endoplasmic reticulum membrane ; Single-pass membrane protein ; Cytoplasmic side .
• Protein Description: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation (Potential)..
• Protein Sequence: MVAKQRIRMANEKHSKNITQRGNVAKTLRPQEEKYPVGPWLLALFVFVVCGSAIFQIIQSIRMGM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Ubiquitination	MANEKHSKNITQRGN HHHHHHCCCCHHHCC	52.68	24816145
21	Methylation	HSKNITQRGNVAKTL HCCCCHHHCCHHHHC	29.97	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SERP2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SERP2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SERP2_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of SERP2_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.