SERB_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SERB_MOUSE
• UniProt AC: Q99LS3
• Protein Name: Phosphoserine phosphatase
• Gene Name: Psph
• Organism: Mus musculus (Mouse).
• Sequence Length: 225
• Protein Description: Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates (By similarity)..
• Protein Sequence: MVSHSELRKLFCSADAVCFDVDSTVIREEGIDELAKFCGVEAAVSEMTRRAMGGALPFKDALTQRLALIQPSRDQVQRLLAEHPPHLTPGIRELVSRLQERNVQVFLISGGFRSIVEHVAAKLNIPTTNVFANRLKFYFNGEYAGFDEMQPTAESGGKGKVIRFLKEKFHFKKIIMIGDGATDMEACPPADAFIGFGGNVIRQQVKDNAKWYITDFVELLGELEE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MVSHSELR -------CCCHHHHH	6.69	-
3	Phosphorylation	-----MVSHSELRKL -----CCCHHHHHHH	21.72	28833060
5	Phosphorylation	---MVSHSELRKLFC ---CCCHHHHHHHHH	30.71	28066266
38	Glutathionylation	IDELAKFCGVEAAVS HHHHHHHHCHHHHHH	6.18	24333276
59	Acetylation	MGGALPFKDALTQRL HCCCCCHHHHHHHHH	39.90	22826441
122	Acetylation	IVEHVAAKLNIPTTN HHHHHHHHCCCCCCH	32.12	22826441
210	Ubiquitination	QQVKDNAKWYITDFV HHHHHHCCEEHHHHH	46.94	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SERB_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SERB_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SERB_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of SERB_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.