SENP_CAEEL - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SENP_CAEEL
• UniProt AC: Q09353
• Protein Name: Sentrin-specific protease
• Gene Name: ulp-1
• Organism: Caenorhabditis elegans.
• Sequence Length: 697
• Subcellular Localization: Nucleus envelope .
• Protein Description: Protease that deconjugates smo-1 from targeted proteins and may catalyze the processing of smo-1 to its mature form..
• Protein Sequence: MSRRSDLSDKDSQSRKRHWLTDQAVTNEEKEQSPTKRTRKTKSQGLGGLFNTFFGMFVSSNSGEKEKTEVSGEVQVQEDDEIIVEGTTRRVAENKKYMIFLNEDAPVRANAGSEENEVIIEKHVQKNVEIRNDEEKQEVQGDLVLTLSSSPKSPKNLEKSFEVQQDDEEPDVLFEKVVKTPNKQLQEARRFQNELIFLNDNPDTPDDVSVISDSRSKEFISPTPDDSVSRPITPSLSSLSNYTSNNVRDYWRRNSAKKPEVLRRVPVRHQFKHSTSVRKMNTIIDLKKIKNHLSSRDRLLQGVVASGQYEAKAISGIVEKKPKKMQRTSSTDILARAKNKIAELGGSRSNTPSLLSREPSIIIDSEESTSSSYRQHARSNSSESDSYRKLNDILSQINSLGIGSAYRGPQRYQNSYQLSKQKEDKLLEEARIREGHRSQTRGDRLEDVRKRLELQGIAIRPKVEKKKVDDFMALPDAADALVERAWSGGNPNEQFVDAFSIQICKKDLATLSGLHWLNDEIINFYLQLICDRSNGDSKYPKIYAFNTFFYSNIVSKGYASVKRWTRKVDIFAFDIVLVPVHLGMHWCMAVIDMGEKKIEFYDSLYDGNTAVLPALRGYLEAESLDKKKTAMNFSGWTIQQMTDIPRQQNGSDCGVFSCQFGEWASRRTTPRFTQKNMPYYRKRMVYEIVSKKLLATI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
33	Phosphorylation	TNEEKEQSPTKRTRK CCHHHHCCCCCCCHH	35.31	21082442
35	Phosphorylation	EEKEQSPTKRTRKTK HHHHCCCCCCCHHHH	38.10	21082442
146	Phosphorylation	VQGDLVLTLSSSPKS ECCCEEEEECCCCCC	19.67	30078680
148	Phosphorylation	GDLVLTLSSSPKSPK CCEEEEECCCCCCCC	24.43	30078680
149	Phosphorylation	DLVLTLSSSPKSPKN CEEEEECCCCCCCCC	54.49	30078680
150	Phosphorylation	LVLTLSSSPKSPKNL EEEEECCCCCCCCCH	32.73	30078680
160	Phosphorylation	SPKNLEKSFEVQQDD CCCCHHHHEECCCCC	19.77	30078680
221	Phosphorylation	SRSKEFISPTPDDSV CCCCCCCCCCCCCCC	28.21	30078680
223	Phosphorylation	SKEFISPTPDDSVSR CCCCCCCCCCCCCCC	32.34	30078680
227	Phosphorylation	ISPTPDDSVSRPITP CCCCCCCCCCCCCCC	29.40	30078680
229	Phosphorylation	PTPDDSVSRPITPSL CCCCCCCCCCCCCCH	35.97	30078680
233	Phosphorylation	DSVSRPITPSLSSLS CCCCCCCCCCHHHHC	14.98	30078680
235	Phosphorylation	VSRPITPSLSSLSNY CCCCCCCCHHHHCCC	32.03	30078680
237	Phosphorylation	RPITPSLSSLSNYTS CCCCCCHHHHCCCCC	33.30	30078680
238	Phosphorylation	PITPSLSSLSNYTSN CCCCCHHHHCCCCCC	40.90	30078680
328	Phosphorylation	KPKKMQRTSSTDILA CCCCCCCCCHHHHHH	15.33	30078680
329	Phosphorylation	PKKMQRTSSTDILAR CCCCCCCCHHHHHHH	33.17	30078680
330	Phosphorylation	KKMQRTSSTDILARA CCCCCCCHHHHHHHH	29.50	19060867
347	Phosphorylation	KIAELGGSRSNTPSL HHHHHCCCCCCCHHH	30.64	28854356
349	Phosphorylation	AELGGSRSNTPSLLS HHHCCCCCCCHHHHC	46.91	19530675
351	Phosphorylation	LGGSRSNTPSLLSRE HCCCCCCCHHHHCCC	18.59	19530675
353	Phosphorylation	GSRSNTPSLLSREPS CCCCCCHHHHCCCCC	39.65	19530675
356	Phosphorylation	SNTPSLLSREPSIII CCCHHHHCCCCCEEE	39.63	19530675
360	Phosphorylation	SLLSREPSIIIDSEE HHHCCCCCEEECCCC	22.97	30078680
381	Phosphorylation	RQHARSNSSESDSYR HHHHHCCCCCCHHHH	36.41	21082442

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SENP_CAEEL !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SENP_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SENP_CAEEL !!

Protein-Protein Interaction

Oops, there are no PPI records of SENP_CAEEL !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.