SEM3F_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SEM3F_HUMAN
• UniProt AC: Q13275
• Protein Name: Semaphorin-3F
• Gene Name: SEMA3F
• Organism: Homo sapiens (Human).
• Sequence Length: 785
• Subcellular Localization: Secreted.
• Protein Description: May play a role in cell motility and cell adhesion..
• Protein Sequence: MLVAGLLLWASLLTGAWPSFPTQDHLPATPRVRLSFKELKATGTAHFFNFLLNTTDYRILLKDEDHDRMYVGSKDYVLSLDLHDINREPLIIHWAASPQRIEECVLSGKDVNGECGNFVRLIQPWNRTHLYVCGTGAYNPMCTYVNRGRRAQATPWTQTQAVRGRGSRATDGALRPMPTAPRQDYIFYLEPERLESGKGKCPYDPKLDTASALINEELYAGVYIDFMGTDAAIFRTLGKQTAMRTDQYNSRWLNDPSFIHAELIPDSAERNDDKLYFFFRERSAEAPQSPAVYARIGRICLNDDGGHCCLVNKWSTFLKARLVCSVPGEDGIETHFDELQDVFVQQTQDVRNPVIYAVFTSSGSVFRGSAVCVYSMADIRMVFNGPFAHKEGPNYQWMPFSGKMPYPRPGTCPGGTFTPSMKSTKDYPDEVINFMRSHPLMYQAVYPLQRRPLVVRTGAPYRLTTIAVDQVDAADGRYEVLFLGTDRGTVQKVIVLPKDDQELEELMLEEVEVFKDPAPVKTMTISSKRQQLYVASAVGVTHLSLHRCQAYGAACADCCLARDPYCAWDGQACSRYTASSKRRSRRQDVRHGNPIRQCRGFNSNANKNAVESVQYGVAGSAAFLECQPRSPQATVKWLFQRDPGDRRREIRAEDRFLRTEQGLLLRALQLSDRGLYSCTATENNFKHVVTRVQLHVLGRDAVHAALFPPLSMSAPPPPGAGPPTPPYQELAQLLAQPEVGLIHQYCQGYWRHVPPSPREAPGAPRSPEPQDQKKPRNRRHHPPDT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	AGLLLWASLLTGAWP HHHHHHHHHHHCCCC	16.60	24043423
14	Phosphorylation	LLWASLLTGAWPSFP HHHHHHHHCCCCCCC	30.10	24043423
19	Phosphorylation	LLTGAWPSFPTQDHL HHHCCCCCCCCCCCC	32.91	24043423
22	Phosphorylation	GAWPSFPTQDHLPAT CCCCCCCCCCCCCCC	44.62	24043423
29	Phosphorylation	TQDHLPATPRVRLSF CCCCCCCCCCEEEEH	15.08	24043423
35	Phosphorylation	ATPRVRLSFKELKAT CCCCEEEEHHHHHHC	24.57	24719451
53	N-linked_Glycosylation	HFFNFLLNTTDYRIL HHHHHHHHCCCEEEE	42.98	UniProtKB CARBOHYD
126	N-linked_Glycosylation	VRLIQPWNRTHLYVC CCCCCCCCCCEEEEC	45.73	UniProtKB CARBOHYD
131	Phosphorylation	PWNRTHLYVCGTGAY CCCCCEEEECCCCCC	6.01	-
144	Phosphorylation	AYNPMCTYVNRGRRA CCCCCCCCCCCCCCC	7.27	-
154	O-linked_Glycosylation	RGRRAQATPWTQTQA CCCCCCCCCCCCCCC	13.79	OGP
157	O-linked_Glycosylation	RAQATPWTQTQAVRG CCCCCCCCCCCCCCC	23.96	OGP
170	O-linked_Glycosylation	RGRGSRATDGALRPM CCCCCCCCCCCCCCC	33.58	OGP
179	O-linked_Glycosylation	GALRPMPTAPRQDYI CCCCCCCCCCCCCEE	42.94	OGP
198	Acetylation	PERLESGKGKCPYDP HHHHHCCCCCCCCCC	65.56	30592291
200	Acetylation	RLESGKGKCPYDPKL HHHCCCCCCCCCCCC	35.21	30592297
209	Phosphorylation	PYDPKLDTASALINE CCCCCCCHHHHHHCH	32.71	28857561
211	Phosphorylation	DPKLDTASALINEEL CCCCCHHHHHHCHHH	26.21	28857561
223	Phosphorylation	EELYAGVYIDFMGTD HHHHCCEEEEECCHH	8.21	28857561
229	Phosphorylation	VYIDFMGTDAAIFRT EEEEECCHHHHHHHH	15.63	28857561
425	Acetylation	TPSMKSTKDYPDEVI CCCCCCCCCCCHHHH	63.46	19814901
437	Phosphorylation	EVINFMRSHPLMYQA HHHHHHHHCCCHHEE	20.05	-
442	Phosphorylation	MRSHPLMYQAVYPLQ HHHCCCHHEEEHHCC	10.87	-
478	Phosphorylation	VDAADGRYEVLFLGT EECCCCCEEEEEEEC	18.87	22461510
485	Phosphorylation	YEVLFLGTDRGTVQK EEEEEEECCCCCEEE	25.35	24719451
522	Phosphorylation	KDPAPVKTMTISSKR CCCCCCCEEEECCCC	21.56	24706070
524	Phosphorylation	PAPVKTMTISSKRQQ CCCCCEEEECCCCHH	23.96	30108239
603	Phosphorylation	RQCRGFNSNANKNAV HHCCCCCCCCCCCHH	34.75	27174698
612	Phosphorylation	ANKNAVESVQYGVAG CCCCHHHHHHHCHHC	14.12	27174698
615	Phosphorylation	NAVESVQYGVAGSAA CHHHHHHHCHHCCEE	16.06	27174698
620	Phosphorylation	VQYGVAGSAAFLECQ HHHCHHCCEEHHHCC	13.49	27174698
713	O-linked_Glycosylation	LFPPLSMSAPPPPGA HCCCCCCCCCCCCCC	33.96	OGP
766	Phosphorylation	EAPGAPRSPEPQDQK CCCCCCCCCCCCCCC	32.34	25159151

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SEM3F_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SEM3F_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SEM3F_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of SEM3F_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.