dbPTM

SEC65_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SEC65_SCHPO
UniProt AC	O94407
Protein Name	Signal recognition particle sec65 subunit
Gene Name	sec65
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	213
Subcellular Localization	Cytoplasm . Nucleus .
Protein Description	Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. It must be involved intimately in the translocation of a wide variety of protein substrates (By similarity)..
Protein Sequence	MISHLLPTTSLTIHMPSIILYPIYFDKSRPRRFRCVPKDKAILNPLAKNIADVVRDLGYKCKLEPLKTHPADWVNPGRVEMVLPEKIQKKYVINEIAKVLLLRPTVKTDPLSLPIQNVPARLPENPPAYPKGVLGNTILPLHSPALSGGGISENMFQEMMQEMQKQPGLAGGMNPMAALAGMGGPAPPMPTPQASSSQRKQKSIEPEYDLDLE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
191	Phosphorylation	GPAPPMPTPQASSSQ CCCCCCCCCCCCCHH	23.06	24763107
203	Phosphorylation	SSQRKQKSIEPEYDL CHHHHHHCCCCCCCC	29.68	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SEC65_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SEC65_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SEC65_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of SEC65_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SEC65_SCHPO

Related Literatures of Post-Translational Modification