dbPTM

SEC5_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SEC5_SCHPO
UniProt AC	O94598
Protein Name	Exocyst complex component sec5
Gene Name	sec5
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	815
Subcellular Localization	Cytoplasm . Localised at the cell tip and barrier septum.
Protein Description	Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane..
Protein Sequence	MSADEEILAHYGLTSLSQDYWTEKPDFAIANASVDVQSPTTGVHHERNRSEDILRTGGATSETTKDASAAGPVTPSFAMKRSQTSVQPSMSSQIAIGGMRNPMATRKIAGTYRDAPDNSMQQTSTGVHRSSSWLTTDGTHQLLSLMETNFNKFIAAKETIDNVYAQIISTLSHAGPAKTMDMCEESISGALQQLQLFNTESTNEVDISYGELLVMRECEALFTYPEKFRLYHKQEKYSLLMQEIENAKKLYEKDRERLAKVNPKLVYLVDHAWEIIQATIDGICASIWNQILQSQGDFAFVVRTLCDLLKLKPNPISGRDPVLYATVSQQKYLYNLMKERFSYFEKIIKSRQEDFSKLSCTRASPMLVWRAVARGCNLDYTLRGRPEVFAGMQLIEWANACVLKIVREIKEVELYAKEFISGIQQASYPEAAKHYGRDPKQMGVVVEKLNSQCLEMVYSFVGERGERLEMDGAFVLIQLHYFQRVADLLPKRIRTVFSMAATRCIVDTWMLQHAPQSKSANIEEMFIVDANENQVLEPELMVVDVLRELNKLYIPPHREEIVREIHHAFYKVLYANARFPSMSVSMANWESDVWSLASSTLIDFVQHRNQHDMKKLASKMTTSLPVFSTSITRSDVLHFVTRLLNLRSRLVPYQKFLLQTFPLNEVSPSLDPRISKSLRNLQDLYKLLAIRDTSFSNTTPSSISKLSIQPPTFQLFSTLETIYLELKDSMPPNEAADWMIATTSCMLAQFALHSPYAFFHDIPSISHFLNKCLPPTILDLLQQIQRKAEASSISPTTETATKTRLKFQFIEMIFS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
50	Phosphorylation	VHHERNRSEDILRTG CCCCCCCCHHHHHCC	43.07	28889911
130	Phosphorylation	TSTGVHRSSSWLTTD CCCCCCCCCCCEECC	17.53	29996109
131	Phosphorylation	STGVHRSSSWLTTDG CCCCCCCCCCEECCC	26.03	29996109
132	Phosphorylation	TGVHRSSSWLTTDGT CCCCCCCCCEECCCH	27.61	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SEC5_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SEC5_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SEC5_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of SEC5_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SEC5_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-50, AND MASSSPECTROMETRY.	18257517 [Abstract]