SEC31_SCHPO - dbPTM
SEC31_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SEC31_SCHPO
UniProt AC O13637
Protein Name Protein transport protein sec31
Gene Name sec31
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 1224
Subcellular Localization Cytoplasmic vesicle, COPII-coated vesicle membrane
Peripheral membrane protein
Cytoplasmic side. Endoplasmic reticulum membrane
Peripheral membrane protein
Cytoplasmic side.
Protein Description Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity)..
Protein Sequence MRLKDISKTATLAWSPRGVNDNQALLALGGYTGTEGSKNSDTLLELWNENPESQKPVGSIDVKTRFYDLAWEKSLDKPMGVIAGSLEDGGIGFWDPAAILKSDEASASIATYKSENGSILGPLDFNRLQPNLLASGDNKGDVWVWDIKHPQQPFALPKQNRSSEVHVVSWNNKVSHILASGNATEYTTVWDVKLKRQVLNLSYLGAAGVSAATGAVNSIAWHPNNATRLATAIDDNRNPIILTWDLRQPTVPQNILTGHQKAALSLSWCPEDPTFLLSSGKDGRAMVWNVETGESLGSFPRSGNWYTKSSWCPSNSNRVAVASLEGKVSIFSIQSTNTDKSQEASIKGATSIDDNEFFNNLPSIAGSQEPSFSLPLAPKWFKVPVGARFGFPNKIVSFSPNSKEVTITSAPDEVEQDEAKSFHSSAKFQTEKEITDFCQKGVEESASEEEAINWKLLMAVSKRASRSKFAELLGYKTLKPKNDEDDSKVDESVAKDSTTPNELSKNANNENYDDDSSFYGKLAESVQEVSIADKKDAEIVKDSFKIFNPEDSDLEKNITEALLTGDVLSAVKACLEEKKISEALFLSTFGGKECRKCVRDAFYELQEHKPSYMRLSACIADNDLQNVVDNAEVSEWKDIFVFICTYATDDEFAPLCSTLGQRLEDLEDEKSIRSAEFCYIASKSLQSYANLWLKQLATSTKTSKAASAYGAYVEQLTKLMDKVSMFRSIVVYKDDELSATKDWKLAGLYEVYIAYAKILSASGKFDDAMSYLNLVPTEFPGAKEEIQRLTMLLEPHAVPPIHQIKQTGYAPVQPKTSQASSILPTVPRTTSYTSPYATTSSHITPADVHPLPPPSTSTTAGWNDAPMLGQLPMRRAAPSMAPVRSPFPGASSAQPAAMSRTSSVSTLPPPPPTASMTASAPAIASPPPPKVGETYHPPTASGTRVPPVQQPSHPNPYTPVAPQSPVAAASRISSSPNMPPSNPYTPIAVASSTVNPAHTYKPHGGSQIVPPPKQPANRVVPLPPTASQRASAYEPPTVSVPSPSALSPSVTPQLPPVSSRLPPVSATRPQIPQPPPVSTALPSSSAVSRPPIATSAGRSSTAASTSAPLTYPAGDRSHIPGNLRPIYEMLNAELQRVSQSLPPQMSRVVHDTEKRLNMLFDRLNSNVLSKPLTDELLALATSLNAHDYQTASNIQTNIVTTLGDQCEHWIVGVTRLITLSKSTT
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
118PhosphorylationTYKSENGSILGPLDF
EEECCCCCEECCCCC		26.6525720772
399PhosphorylationPNKIVSFSPNSKEVT
CCCEEEECCCCCEEE		18.7028889911
487PhosphorylationPKNDEDDSKVDESVA
CCCCCCCCCCCHHHH		47.0724763107
497PhosphorylationDESVAKDSTTPNELS
CHHHHCCCCCHHHHH		33.2121712547
498PhosphorylationESVAKDSTTPNELSK
HHHHCCCCCHHHHHC		57.3027738172
499PhosphorylationSVAKDSTTPNELSKN
HHHCCCCCHHHHHCC		28.2428889911
516PhosphorylationNENYDDDSSFYGKLA
CCCCCCCCCHHHHHH		29.3729996109
517PhosphorylationENYDDDSSFYGKLAE
CCCCCCCCHHHHHHH		29.4928889911
525PhosphorylationFYGKLAESVQEVSIA
HHHHHHHHHEEEECC		24.4028889911
530PhosphorylationAESVQEVSIADKKDA
HHHHEEEECCCHHCH		16.0024763107
674PhosphorylationEDEKSIRSAEFCYIA
CCHHHHCHHHHHHHH		30.4025720772
839PhosphorylationYTSPYATTSSHITPA
CCCCCCCCCCCCCHH		21.7627738172
879PhosphorylationPMRRAAPSMAPVRSP
CCCCCCCCCCCCCCC		23.8929996109
885PhosphorylationPSMAPVRSPFPGASS
CCCCCCCCCCCCCCC		31.0025720772
891PhosphorylationRSPFPGASSAQPAAM
CCCCCCCCCCCCCCC		31.9327738172
892PhosphorylationSPFPGASSAQPAAMS
CCCCCCCCCCCCCCC		30.3225720772
899PhosphorylationSAQPAAMSRTSSVST
CCCCCCCCCCCCCCC		27.9028889911
901PhosphorylationQPAAMSRTSSVSTLP
CCCCCCCCCCCCCCC		20.3229996109
902PhosphorylationPAAMSRTSSVSTLPP
CCCCCCCCCCCCCCC		27.8625720772
903PhosphorylationAAMSRTSSVSTLPPP
CCCCCCCCCCCCCCC		21.3425720772
905PhosphorylationMSRTSSVSTLPPPPP
CCCCCCCCCCCCCCC		26.6129996109
906PhosphorylationSRTSSVSTLPPPPPT
CCCCCCCCCCCCCCC		40.9229996109
913PhosphorylationTLPPPPPTASMTASA
CCCCCCCCCCCCCCC		36.8229996109
915PhosphorylationPPPPPTASMTASAPA
CCCCCCCCCCCCCCC		21.1029996109
917PhosphorylationPPPTASMTASAPAIA
CCCCCCCCCCCCCCC		18.2425720772
919PhosphorylationPTASMTASAPAIASP
CCCCCCCCCCCCCCC		26.1429996109
925PhosphorylationASAPAIASPPPPKVG
CCCCCCCCCCCCCCC		31.6529996109
952PhosphorylationVPPVQQPSHPNPYTP
CCCCCCCCCCCCCCC		47.4328889911
957PhosphorylationQPSHPNPYTPVAPQS
CCCCCCCCCCCCCCC		30.2529996109
958PhosphorylationPSHPNPYTPVAPQSP
CCCCCCCCCCCCCCH		16.7329996109
964PhosphorylationYTPVAPQSPVAAASR
CCCCCCCCHHHHHHC		21.9328889911
970PhosphorylationQSPVAAASRISSSPN
CCHHHHHHCCCCCCC		25.9729996109
973PhosphorylationVAAASRISSSPNMPP
HHHHHCCCCCCCCCC		24.5329996109
974PhosphorylationAAASRISSSPNMPPS
HHHHCCCCCCCCCCC		47.6629996109
975PhosphorylationAASRISSSPNMPPSN
HHHCCCCCCCCCCCC		17.3229996109
981PhosphorylationSSPNMPPSNPYTPIA
CCCCCCCCCCCCCEE		44.5629996109
985PhosphorylationMPPSNPYTPIAVASS
CCCCCCCCCEEEEEC		14.9629996109
991PhosphorylationYTPIAVASSTVNPAH
CCCEEEEECCCCCCC		21.6829996109
992PhosphorylationTPIAVASSTVNPAHT
CCEEEEECCCCCCCC		27.0029996109
993PhosphorylationPIAVASSTVNPAHTY
CEEEEECCCCCCCCC		23.0829996109
999PhosphorylationSTVNPAHTYKPHGGS
CCCCCCCCCCCCCCC		35.0329996109
1031PhosphorylationPTASQRASAYEPPTV
CCHHHHCCCCCCCEE		33.3129996109
1039PhosphorylationAYEPPTVSVPSPSAL
CCCCCEEECCCHHHC		30.6825720772
1042PhosphorylationPPTVSVPSPSALSPS
CCEEECCCHHHCCCC		29.3628889911
1044PhosphorylationTVSVPSPSALSPSVT
EEECCCHHHCCCCCC		46.2928889911
1047PhosphorylationVPSPSALSPSVTPQL
CCCHHHCCCCCCCCC		18.1625720772
1049PhosphorylationSPSALSPSVTPQLPP
CHHHCCCCCCCCCCC		34.9429996109
1051PhosphorylationSALSPSVTPQLPPVS
HHCCCCCCCCCCCCC		15.0625720772
1101PhosphorylationTSAGRSSTAASTSAP
CCCCCCCCCCCCCCC		27.7325720772
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SEC31_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SEC31_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SEC31_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of SEC31_SCHPO !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SEC31_SCHPO

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-499; SER-1042 ANDSER-1044, AND MASS SPECTROMETRY.

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