dbPTM

SDHA_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SDHA_SCHPO
UniProt AC	Q9UTJ7
Protein Name	Probable succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Gene Name	sdh1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	641
Subcellular Localization	Mitochondrion inner membrane Peripheral membrane protein Matrix side .
Protein Description	Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q)..
Protein Sequence	MLRFRKVAPSLKNGGNLKLFSTSSTLKKIASSQPLRAKQVSTSESVKYPVIDHTYDAIVVGAGGAGLRATFGLAEAGFNTACITKLFPTRSHTVAAQGGINAALGNMTKDDWRWHFYDTVKGSDWLGDQDAIHYMTKEAPKAVLELEHFGVPFSRTKEGKIYQRAFGGQSLEYGKGGQAYRCAAVADRTGHSILHTLYGQSLKHNTNFFIEYFAMDLIMEGGECRGVIAMNLEDGSIHRFRAHKTILATGGYGRAYFSCTSAHTCTGDGNAMVSRAGLPLQDLEFVQFHPTGIYGAGCLITEGCRGEGGYLLNSKGERFMERYAPTAKDLASRDVVSRAMTVEIREGRGVGPEKDHCYLQLSHLPAEILKERLPGISETAAIFAGVDVTKEPIPVLPTVHYNMGGIPTRFTGEVLTIDENGKDKIVPGLYAAGEAACVSVHGGNRLGANSLLDIVVFGRACALHIKDTLEPNTPHKPLAADAGLDSLKFLDQIRTSQGPKHTSEIRLDMQKTMQRDVSVFRMEETLQEGVKNIARVDGTYKDIGIRDRGLIWNTDLVEALELRNLLTCAVQTANAALNRKESRGAHAREDYPERDDKNWIKHTLTWQHKTGDPVTLKYRAVTRTTMDENEVKPVPPFKRVY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
92	Tele-8alpha-FAD histidine	KLFPTRSHTVAAQGG ECCCCCCHHHHHCCC		-
92	Other	KLFPTRSHTVAAQGG ECCCCCCHHHHHCCC		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SDHA_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SDHA_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SDHA_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of SDHA_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SDHA_SCHPO

Related Literatures of Post-Translational Modification