| UniProt ID | SDC3_RAT | |
|---|---|---|
| UniProt AC | P33671 | |
| Protein Name | Syndecan-3 | |
| Gene Name | Sdc3 | |
| Organism | Rattus norvegicus (Rat). | |
| Sequence Length | 442 | |
| Subcellular Localization |
Membrane Single-pass type I membrane protein. |
|
| Protein Description | Cell surface proteoglycan that may bear heparan sulfate. May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism (By similarity).. | |
| Protein Sequence | MKPGPPRRGTAQGQRVDTATHGPGARGLLLPPLLLLLLAGRAAGAQRWRNENFERPVDLEGSGDDDSFPDDELDDLYSGSGSGYFEQESGLETAMRFIPDIALAAPTAPAMLPTTVIQPVDTPFEELLSEHPGPEPVTSPPLVTEVTEVVEEPSQRATTISTTTSTTAATTTGAPTMATAPATAATTAPSTPAAPPATATTADIRTTGIQGLLPLPLTTAATAKATTPAVPSPPTTVTTLDTEAPTPRLVNTATSRPRALPRPVTTQEPEVAERSTLPLGTTAPGPTEVAQTPTPESLLTTTQDEPEVPVSGGPSGDFELQEETTQPDTANEVVAVEGAAAKPSPPLGTLPKGARPGLGLHDNAIDSGSSAAQLPQKSILERKEVLVAVIVGGVVGALFAAFLVTLLIYRMKKKDEGSYTLEEPKQASVTYQKPDKQEEFYA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 78 | O-linked_Glycosylation | DELDDLYSGSGSGYF HHHHHHHCCCCCCCC | 33.51 | - | |
| 80 | O-linked_Glycosylation | LDDLYSGSGSGYFEQ HHHHHCCCCCCCCCC | 24.68 | - | |
| 82 | O-linked_Glycosylation | DLYSGSGSGYFEQES HHHCCCCCCCCCCCC | 31.83 | - | |
| 89 | O-linked_Glycosylation | SGYFEQESGLETAMR CCCCCCCCCHHHHHH | 48.66 | - | |
| 315 | O-linked_Glycosylation | VPVSGGPSGDFELQE CCCCCCCCCCCEECC | 55.03 | - | |
| 367 | O-linked_Glycosylation | LHDNAIDSGSSAAQL CCCCCCCCCCCHHHC | 34.17 | - | |
| 409 | Phosphorylation | FLVTLLIYRMKKKDE HHHHHHHHHHHHCCC | 12.48 | - | |
| 419 | Phosphorylation | KKKDEGSYTLEEPKQ HHCCCCCCCCCCCCC | 26.63 | - | |
| 428 | Phosphorylation | LEEPKQASVTYQKPD CCCCCCCEEEEECCC | 16.70 | 30240740 | |
| 430 | Phosphorylation | EPKQASVTYQKPDKQ CCCCCEEEEECCCCC | 20.10 | 30181290 | |
| 431 | Phosphorylation | PKQASVTYQKPDKQE CCCCEEEEECCCCCC | 16.63 | - | |
| 441 | Phosphorylation | PDKQEEFYA------ CCCCCCCCC------ | 18.06 | 9388509 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
| 441 | Y | Phosphorylation | Kinase | EPHB1 | P54762 | PSP |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SDC3_RAT !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SDC3_RAT !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of SDC3_RAT !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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