SCX_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SCX_MOUSE
• UniProt AC: Q64124
• Protein Name: Basic helix-loop-helix transcription factor scleraxis
• Gene Name: Scx
• Organism: Mus musculus (Mouse).
• Sequence Length: 207
• Subcellular Localization: Nucleus .
• Protein Description: Plays an early essential role in mesoderm formation, as well as a later role in formation of somite-derived chondrogenic lineages..
• Protein Sequence: MSFAMLRSAPPPGRYLYPEVSPLSEDEDRGSESSGSDEKPCRVHAARCGLQGARRRAGGRRAAGSGPGPGGRPGREPRQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLVGEACGDGQPCHSGPAFFHSGRAGSPLPPPPPPPPLARDGGENTQPKQICTFCLSNQRKLSKDRDRKTAIRS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSFAMLRSA ------CCCCCCCCC	23.01	29472430
103	Phosphorylation	TAFTALRTLIPTEPA HHHHHHHHHCCCCCC	29.86	21454597
107	Phosphorylation	ALRTLIPTEPADRKL HHHHHCCCCCCCCCC	47.83	21454597
160	Phosphorylation	FHSGRAGSPLPPPPP CCCCCCCCCCCCCCC	23.44	26239621

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SCX_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SCX_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SCX_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of SCX_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.