SCX_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SCX_HUMAN
• UniProt AC: Q7RTU7
• Protein Name: Basic helix-loop-helix transcription factor scleraxis
• Gene Name: SCX
• Organism: Homo sapiens (Human).
• Sequence Length: 201
• Subcellular Localization: Nucleus .
• Protein Description: Plays an early essential role in mesoderm formation, as well as a later role in formation of somite-derived chondrogenic lineages..
• Protein Sequence: MSFATLRPAPPGRYLYPEVSPLSEDEDRGSDSSGSDEKPCRVHAARCGLQGARRRAGGRRAGGGGPGGRPGREPRQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGEACGDGQPCHSGPAFFHAARAGSPPPPPPPPPARDGENTQPKQICTFCLSNQRKLSKDRDRKTAIRS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MSFATLRPAPPG ---CCCCCCCCCCCC	22.68	24719451
20	Phosphorylation	RYLYPEVSPLSEDED CCCCCCCCCCCCCCC	20.61	24719451
30	Phosphorylation	SEDEDRGSDSSGSDE CCCCCCCCCCCCCCC	34.90	-
32	Phosphorylation	DEDRGSDSSGSDEKP CCCCCCCCCCCCCCC	37.99	-
33	Phosphorylation	EDRGSDSSGSDEKPC CCCCCCCCCCCCCCH	47.51	-
35	Phosphorylation	RGSDSSGSDEKPCRV CCCCCCCCCCCCHHH	44.54	-
100	Phosphorylation	TAFTALRTLIPTEPA HHHHHHHHHCCCCCC	29.86	-
157	Phosphorylation	FHAARAGSPPPPPPP HHHHHCCCCCCCCCC	32.99	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SCX_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SCX_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SCX_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of SCX_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.