SCR1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SCR1_SCHPO
• UniProt AC: O14335
• Protein Name: DNA-binding protein scr1
• Gene Name: scr1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 565
• Subcellular Localization: Nucleus .
• Protein Description: Involved in carbon catabolite repression. Represses the transcription of various genes including the inv1 gene..
• Protein Sequence: MSEATTATTTGKPSRSTKNPDAPRPYKCPLCTKAFYRLEHQTRHIRTHTGEKPHVCTFPGCAKRFSRSDELTRHARIHTNANSRRNAAAAAAANNSARSSNSPAGNLEPSTNNAGVHMTNASMNPNVNPSYPVFIPQVGMSVAPPVATAAVSMSYPHHYSASVQQQQATFVSNGQPHNLPAQAQPATIYGIPDALHTTQNGTTIHVTGTPPGAVSQRSEPDSRLSSMNEMQLLASAAANQLDAAPRITPTKSSGVNLMPLSNAPSPPKQMNVVGSLPSSSNTSPNHLASVPNRGLTSNSSTGSFTKYTNGSSNSLYSNSSMQTPYLPSKSNSSTSLHSMYGVGTTAYAPQSLRYAHYNYLPYSRPSVSNGFDDDSSSSDFAHFRYQRRSRPVSPCSTAPSSPTFSTRSFSPTPDVTPLVTPAHSPRLRPMDDPSCVQLPSIRSLSLRPSQVPLIPPLKCDPNAFSASTPASGAVSRTPSSVSLSSLSNVNSSMPHKPASQSNVGPVRISSNRRSRKFSSSSRVSVSNLLAGSPPSPSSSTKSASSSYSTTTPAFSIGPLTPMTKP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
248	Phosphorylation	LDAAPRITPTKSSGV HCCCCCCCCCCCCCC	26.62	29996109
250	Phosphorylation	AAPRITPTKSSGVNL CCCCCCCCCCCCCCE	34.60	29996109
261	Phosphorylation	GVNLMPLSNAPSPPK CCCEEECCCCCCCCC	25.69	24763107
265	Phosphorylation	MPLSNAPSPPKQMNV EECCCCCCCCCCCCC	51.96	28889911
275	Phosphorylation	KQMNVVGSLPSSSNT CCCCCCCCCCCCCCC	26.04	25720772
278	Phosphorylation	NVVGSLPSSSNTSPN CCCCCCCCCCCCCCC	52.25	21712547
279	Phosphorylation	VVGSLPSSSNTSPNH CCCCCCCCCCCCCCC	26.18	25720772
280	Phosphorylation	VGSLPSSSNTSPNHL CCCCCCCCCCCCCCC	48.76	29996109
282	Phosphorylation	SLPSSSNTSPNHLAS CCCCCCCCCCCCCCC	47.73	29996109
283	Phosphorylation	LPSSSNTSPNHLASV CCCCCCCCCCCCCCC	28.14	25720772
289	Phosphorylation	TSPNHLASVPNRGLT CCCCCCCCCCCCCCC	44.46	29996109
299	Phosphorylation	NRGLTSNSSTGSFTK CCCCCCCCCCCCCEE	29.10	25720772
300	Phosphorylation	RGLTSNSSTGSFTKY CCCCCCCCCCCCEEE	40.83	25720772
301	Phosphorylation	GLTSNSSTGSFTKYT CCCCCCCCCCCEEEC	36.34	29996109
303	Phosphorylation	TSNSSTGSFTKYTNG CCCCCCCCCEEECCC	29.81	25720772
305	Phosphorylation	NSSTGSFTKYTNGSS CCCCCCCEEECCCCC	25.49	25720772
311	Phosphorylation	FTKYTNGSSNSLYSN CEEECCCCCCCCCCC	28.54	25720772
312	Phosphorylation	TKYTNGSSNSLYSNS EEECCCCCCCCCCCC	31.66	25720772
330	Phosphorylation	TPYLPSKSNSSTSLH CCCCCCCCCCCCCCC	46.40	25720772
332	Phosphorylation	YLPSKSNSSTSLHSM CCCCCCCCCCCCCCC	41.92	25720772
333	Phosphorylation	LPSKSNSSTSLHSMY CCCCCCCCCCCCCCC	26.68	25720772
334	Phosphorylation	PSKSNSSTSLHSMYG CCCCCCCCCCCCCCC	34.82	25720772
335	Phosphorylation	SKSNSSTSLHSMYGV CCCCCCCCCCCCCCC	26.49	25720772
338	Phosphorylation	NSSTSLHSMYGVGTT CCCCCCCCCCCCCCC	20.99	25720772
340	Phosphorylation	STSLHSMYGVGTTAY CCCCCCCCCCCCCEE	16.21	25720772
389	Phosphorylation	HFRYQRRSRPVSPCS HHHCCCCCCCCCCCC	43.03	25720772
393	Phosphorylation	QRRSRPVSPCSTAPS CCCCCCCCCCCCCCC	23.91	29996109
396	Phosphorylation	SRPVSPCSTAPSSPT CCCCCCCCCCCCCCC	30.87	25720772
397	Phosphorylation	RPVSPCSTAPSSPTF CCCCCCCCCCCCCCC	49.67	29996109
400	Phosphorylation	SPCSTAPSSPTFSTR CCCCCCCCCCCCCCC	46.62	29996109
401	Phosphorylation	PCSTAPSSPTFSTRS CCCCCCCCCCCCCCC	27.22	29996109
403	Phosphorylation	STAPSSPTFSTRSFS CCCCCCCCCCCCCCC	31.97	29996109
405	Phosphorylation	APSSPTFSTRSFSPT CCCCCCCCCCCCCCC	25.95	25720772
406	Phosphorylation	PSSPTFSTRSFSPTP CCCCCCCCCCCCCCC	26.58	25720772
408	Phosphorylation	SPTFSTRSFSPTPDV CCCCCCCCCCCCCCC	30.11	29996109
410	Phosphorylation	TFSTRSFSPTPDVTP CCCCCCCCCCCCCCC	29.16	28889911
412	Phosphorylation	STRSFSPTPDVTPLV CCCCCCCCCCCCCCC	30.81	25720772
416	Phosphorylation	FSPTPDVTPLVTPAH CCCCCCCCCCCCCCC	20.48	25720772
420	Phosphorylation	PDVTPLVTPAHSPRL CCCCCCCCCCCCCCC	23.57	29996109
424	Phosphorylation	PLVTPAHSPRLRPMD CCCCCCCCCCCCCCC	17.52	28889911
443	Phosphorylation	VQLPSIRSLSLRPSQ CCCCCCCEECCCHHH	22.20	25720772
445	Phosphorylation	LPSIRSLSLRPSQVP CCCCCEECCCHHHCC	24.47	25720772
449	Phosphorylation	RSLSLRPSQVPLIPP CEECCCHHHCCCCCC	37.06	25720772
477	Phosphorylation	ASGAVSRTPSSVSLS CCCCCCCCCCCCCHH	21.73	25720772
479	Phosphorylation	GAVSRTPSSVSLSSL CCCCCCCCCCCHHHH	42.64	25720772
480	Phosphorylation	AVSRTPSSVSLSSLS CCCCCCCCCCHHHHC	19.54	27738172
482	Phosphorylation	SRTPSSVSLSSLSNV CCCCCCCCHHHHCCC	25.20	25720772
485	Phosphorylation	PSSVSLSSLSNVNSS CCCCCHHHHCCCCCC	40.90	25720772
491	Phosphorylation	SSLSNVNSSMPHKPA HHHCCCCCCCCCCCC	24.59	25720772
518	Phosphorylation	NRRSRKFSSSSRVSV CCCCCCCCCCCCEEH	32.14	25720772
520	Phosphorylation	RSRKFSSSSRVSVSN CCCCCCCCCCEEHHH	22.44	25720772
521	Phosphorylation	SRKFSSSSRVSVSNL CCCCCCCCCEEHHHH	38.35	25720772
524	Phosphorylation	FSSSSRVSVSNLLAG CCCCCCEEHHHHHCC	20.79	29996109
526	Phosphorylation	SSSRVSVSNLLAGSP CCCCEEHHHHHCCCC	17.79	28889911
532	Phosphorylation	VSNLLAGSPPSPSSS HHHHHCCCCCCCCCC	28.20	25720772
535	Phosphorylation	LLAGSPPSPSSSTKS HHCCCCCCCCCCCCC	40.58	25720772
537	Phosphorylation	AGSPPSPSSSTKSAS CCCCCCCCCCCCCCC	41.06	25720772
538	Phosphorylation	GSPPSPSSSTKSASS CCCCCCCCCCCCCCC	45.47	25720772
539	Phosphorylation	SPPSPSSSTKSASSS CCCCCCCCCCCCCCC	44.16	25720772
542	Phosphorylation	SPSSSTKSASSSYST CCCCCCCCCCCCCCC	33.21	21712547
544	Phosphorylation	SSSTKSASSSYSTTT CCCCCCCCCCCCCCC	27.23	21712547
548	Phosphorylation	KSASSSYSTTTPAFS CCCCCCCCCCCCCEE	22.64	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SCR1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SCR1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SCR1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TUP12_SCHPO	tup12	genetic	11238405
TUP11_SCHPO	tup11	genetic	11238405

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.