SCPDL_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SCPDL_RAT
• UniProt AC: Q6AY30
• Protein Name: Saccharopine dehydrogenase-like oxidoreductase
• Gene Name: Sccpdh
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 429
• Protein Sequence: MATEQRPFQLVVFGASGFTGQFVTEEVAREQMASEQSSRLPWAVAGRSKEKLQQVLEKAAQKLGRATLSSEVGIIICDISNPASLDEMAKKATLVLNCVGPYRFYGEPVVKACIENGTSCIDICGEPQFLELMHVKYHEKAAEKGVYIIGSSGFDSIPADLGVLYTRNQMNGTLTAVESFLTINSGPEGLCIHDGTWKSAIYGFGDKGSLRKLRSVSNLKPVPVIGSKLKRRWPVSYCRELNSYAIPFLGSDMSVVKRTQRYLHENLEDSPVQYAAYITVGGITSVIKLMFAGLFFLFFVKFSIGRQLLVKFPWLFSFGYFSKRGPTQKQMDESSFTMTFFGQGYSHGVSAEKNKPNIRICTQVKGPEAGYVATPIAMVQAAVTFLNDASDLPKGGGVFTPGAAFSRTKLIDRLNQHGIQFSVISSSEV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MATEQRPFQ ------CCCCCCCEE	21.61	-
51	Acetylation	VAGRSKEKLQQVLEK HCCCCHHHHHHHHHH	56.16	22902405
140	Ubiquitination	MHVKYHEKAAEKGVY HHHHHHHHHHHCCEE	39.31	-
202	Phosphorylation	GTWKSAIYGFGDKGS CCCCEEEECCCCHHH	13.20	25575281
207	Acetylation	AIYGFGDKGSLRKLR EEECCCCHHHHHHHH	51.26	22902405
209	Phosphorylation	YGFGDKGSLRKLRSV ECCCCHHHHHHHHCC	30.64	29779826
215	Phosphorylation	GSLRKLRSVSNLKPV HHHHHHHCCCCCCCC	40.09	23991683
217	Phosphorylation	LRKLRSVSNLKPVPV HHHHHCCCCCCCCCC	37.38	23991683
220	Acetylation	LRSVSNLKPVPVIGS HHCCCCCCCCCCCCC	48.49	22902405
220	Ubiquitination	LRSVSNLKPVPVIGS HHCCCCCCCCCCCCC	48.49	-
227	Phosphorylation	KPVPVIGSKLKRRWP CCCCCCCCCCCCCCC	24.56	28689409
228	Acetylation	PVPVIGSKLKRRWPV CCCCCCCCCCCCCCH	53.46	22902405
257	Acetylation	GSDMSVVKRTQRYLH CCCHHHHHHHHHHHH	47.80	22902405
334	Phosphorylation	TQKQMDESSFTMTFF CHHHCCCCCEEEEEE	26.87	28689409
345	Phosphorylation	MTFFGQGYSHGVSAE EEEECCCCCCCCCCC	6.93	28689409

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SCPDL_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SCPDL_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SCPDL_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of SCPDL_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.