SCAM3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SCAM3_MOUSE
• UniProt AC: O35609
• Protein Name: Secretory carrier-associated membrane protein 3
• Gene Name: Scamp3
• Organism: Mus musculus (Mouse).
• Sequence Length: 349
• Subcellular Localization: Membrane; Multi-pass membrane protein.
• Protein Description: Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface..
• Protein Sequence: MAQSRDTGNPFPDSGELDNPFQDPAVIQHRPSQQYATLDVYNPFENREPPPAYEPPAPAPAPLPPPSAPSVQSSRKLSPTEPRNYGSYSTQASAAAATAELLKKQEELNRKAEELDRRERELQHVALGGAGTRQNNWPPLPSFCPVKPCFFQDISMEIPQEFQKTVSTMYYLWMCSTLALLLNFFACLARFCVDTGSGSGFGLSMLWLLLFTPCSFVCWYRPMYKAFRSDSSFNFFVFFFIFFVQDVFFVLQAIGIPGWGFSGWVTALVVVGSKPAVAVLMLLVALLFTGIAVLGIVMLKRIHSLYRQTGASFQKAQQEFAAGVFSNPAVRTAAANAAAGAAENAFRAP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MAQSRDTGNPFPDS -CCCCCCCCCCCCCC	37.44	23984901
14	Phosphorylation	TGNPFPDSGELDNPF CCCCCCCCCCCCCCC	34.11	25159016
32	Phosphorylation	AVIQHRPSQQYATLD HHHCCCCCCCEEEEE	29.85	26239621
35	Phosphorylation	QHRPSQQYATLDVYN CCCCCCCEEEEEECC	8.23	26239621
37	Phosphorylation	RPSQQYATLDVYNPF CCCCCEEEEEECCCC	20.68	26239621
41	Phosphorylation	QYATLDVYNPFENRE CEEEEEECCCCCCCC	19.45	23984901
53	Phosphorylation	NREPPPAYEPPAPAP CCCCCCCCCCCCCCC	34.44	25159016
74	Phosphorylation	SAPSVQSSRKLSPTE CCCCCCCCCCCCCCC	19.15	-
76	Malonylation	PSVQSSRKLSPTEPR CCCCCCCCCCCCCCC	56.09	26320211
78	Phosphorylation	VQSSRKLSPTEPRNY CCCCCCCCCCCCCCC	32.58	26824392
80	Phosphorylation	SSRKLSPTEPRNYGS CCCCCCCCCCCCCCC	56.07	22942356
85	Phosphorylation	SPTEPRNYGSYSTQA CCCCCCCCCCHHHHH	14.55	25521595
87	Phosphorylation	TEPRNYGSYSTQASA CCCCCCCCHHHHHHH	12.92	21082442
88	Phosphorylation	EPRNYGSYSTQASAA CCCCCCCHHHHHHHH	16.04	26239621
89	Phosphorylation	PRNYGSYSTQASAAA CCCCCCHHHHHHHHH	18.75	26239621
90	Phosphorylation	RNYGSYSTQASAAAA CCCCCHHHHHHHHHH	21.66	26239621
93	Phosphorylation	GSYSTQASAAAATAE CCHHHHHHHHHHHHH	14.50	28833060
103	Ubiquitination	AATAELLKKQEELNR HHHHHHHHHHHHHHH	66.10	-
104	Ubiquitination	ATAELLKKQEELNRK HHHHHHHHHHHHHHH	64.01	-
304	Phosphorylation	VMLKRIHSLYRQTGA HHHHHHHHHHHHHCC	25.40	-
306	Phosphorylation	LKRIHSLYRQTGASF HHHHHHHHHHHCCHH	12.04	-
309	Phosphorylation	IHSLYRQTGASFQKA HHHHHHHHCCHHHHH	26.22	28285833
312	Phosphorylation	LYRQTGASFQKAQQE HHHHHCCHHHHHHHH	29.56	28285833
315	Ubiquitination	QTGASFQKAQQEFAA HHCCHHHHHHHHHHH	46.26	-
326	Phosphorylation	EFAAGVFSNPAVRTA HHHHCCCCCHHHHHH	39.23	24759943

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SCAM3_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SCAM3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SCAM3_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of SCAM3_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Solid tumor proteome and phosphoproteome analysis by high resolutionmass spectrometry.";
Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J.,Faessler R., Mann M.;
J. Proteome Res. 7:5314-5326(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-78, AND MASSSPECTROMETRY.
PubMed: 19367708