SCAM1_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SCAM1_RAT
• UniProt AC: P56603
• Protein Name: Secretory carrier-associated membrane protein 1
• Gene Name: Scamp1
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 338
• Subcellular Localization: Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein.
• Protein Description: Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface..
• Protein Sequence: MSDFDSNPFADPDLNNPFKDPSVTQVTRNVPPGLDEYNPFSDSRTPPPGGVKMPNVPNTQPAIMKPTEEHPAYTQITKEHALAQAELLKRQEELERKAAELDRREREMQNLSQHGRKNNWPPLPSNFPVGPCFYQDFSVDIPVEFQKTVKLMYYLWMFHAVTLFLNIFGCLAWFCVDSSRAVDFGLSILWFLLFTPCSFVCWYRPLYGAFRSDSSFRFFVFFFVYICQFAVHVLQAAGFHNWGNCGWISSLTGLNKNIPVGIMMIIIAALFTASAVISLVMFKKVHGLYRTTGASFEKAQQEFATGVMSNKTVQTAAANAASTAATSAAQNAFKGNQM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSDFDSNPF ------CCCCCCCCC	47.16	-
2	Phosphorylation	------MSDFDSNPF ------CCCCCCCCC	47.16	27097102
6	Phosphorylation	--MSDFDSNPFADPD --CCCCCCCCCCCCC	46.53	27097102
37	Phosphorylation	VPPGLDEYNPFSDSR CCCCCCCCCCCCCCC	28.00	22276854
41	Phosphorylation	LDEYNPFSDSRTPPP CCCCCCCCCCCCCCC	35.61	25403869
43	Phosphorylation	EYNPFSDSRTPPPGG CCCCCCCCCCCCCCC	36.53	30240740
45	Phosphorylation	NPFSDSRTPPPGGVK CCCCCCCCCCCCCCC	44.06	30240740
67	Phosphorylation	QPAIMKPTEEHPAYT CCCCCCCCCCCCCHH	48.78	27097102
73	Phosphorylation	PTEEHPAYTQITKEH CCCCCCCHHHHCHHH	12.02	27097102
74	Phosphorylation	TEEHPAYTQITKEHA CCCCCCHHHHCHHHH	18.66	27097102
77	Phosphorylation	HPAYTQITKEHALAQ CCCHHHHCHHHHHHH	22.14	27097102
89	Ubiquitination	LAQAELLKRQEELER HHHHHHHHHHHHHHH	65.74	-
112	Phosphorylation	EREMQNLSQHGRKNN HHHHHHHHHHCHHCC	27.90	25403869
298	Ubiquitination	TTGASFEKAQQEFAT CCCCCHHHHHHHHHH	49.86	-
334	Ubiquitination	SAAQNAFKGNQM--- HHHHHHHCCCCC---	55.32	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SCAM1_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SCAM1_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SCAM1_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of SCAM1_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.