SCAM1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SCAM1_MOUSE
• UniProt AC: Q8K021
• Protein Name: Secretory carrier-associated membrane protein 1
• Gene Name: Scamp1
• Organism: Mus musculus (Mouse).
• Sequence Length: 338
• Subcellular Localization: Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein.
• Protein Description: Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface (By similarity)..
• Protein Sequence: MSDFDSNPFADPDLNNPFKDPSVTQVTRNVPPGLDEYNPFSDSRTPPPGSVKMPNVPNTQPAIMKPTEEHPAYTQITKEHALAQAELLKRQEELERKAAELDRREREMQNLSQHGRKNNWPPLPSNFPVGPCFYQDFSVDIPVEFQKTVKLMYYLWMFHAVTLFLNIFGCLAWFCVDSSRAVDFGLSILWFLLFTPCSFVCWYRPLYGAFRSDSSFRFFVFFFVYICQFAVHVLQAAGFHNWGNCGWISSLTGLNKNIPVGIMMIIIAALFTASAVISLVMFKKVHGLYRTTGASFEKAQQEFATGVMSNKTVQTAAANAASTAATSAAQNAFKGNQM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSDFDSNPF ------CCCCCCCCC	47.16	30352176
2	Acetylation	------MSDFDSNPF ------CCCCCCCCC	47.16	-
6	Phosphorylation	--MSDFDSNPFADPD --CCCCCCCCCCCCC	46.53	23984901
37	Phosphorylation	VPPGLDEYNPFSDSR CCCCCCCCCCCCCCC	28.00	25159016
41	Phosphorylation	LDEYNPFSDSRTPPP CCCCCCCCCCCCCCC	35.61	24925903
43	Phosphorylation	EYNPFSDSRTPPPGS CCCCCCCCCCCCCCC	36.53	25521595
45	Phosphorylation	NPFSDSRTPPPGSVK CCCCCCCCCCCCCCC	44.06	25521595
50	Phosphorylation	SRTPPPGSVKMPNVP CCCCCCCCCCCCCCC	25.08	24925903
59	Phosphorylation	KMPNVPNTQPAIMKP CCCCCCCCCCCCCCC	29.84	23375375
59	O-linked_Glycosylation	KMPNVPNTQPAIMKP CCCCCCCCCCCCCCC	29.84	22517741
65	Ubiquitination	NTQPAIMKPTEEHPA CCCCCCCCCCCCCCC	42.55	-
73	Phosphorylation	PTEEHPAYTQITKEH CCCCCCCHHHHCHHH	12.02	25195567
74	Phosphorylation	TEEHPAYTQITKEHA CCCCCCHHHHCHHHH	18.66	29514104
77	Phosphorylation	HPAYTQITKEHALAQ CCCHHHHCHHHHHHH	22.14	29514104
78	Ubiquitination	PAYTQITKEHALAQA CCHHHHCHHHHHHHH	49.48	-
89	Ubiquitination	LAQAELLKRQEELER HHHHHHHHHHHHHHH	65.74	-
112	Phosphorylation	EREMQNLSQHGRKNN HHHHHHHHHHCHHCC	27.90	25521595
298	Ubiquitination	TTGASFEKAQQEFAT CCCCCHHHHHHHHHH	49.86	-
309	Phosphorylation	EFATGVMSNKTVQTA HHHHCCCCCHHHHHH	32.54	29899451
311	Ubiquitination	ATGVMSNKTVQTAAA HHCCCCCHHHHHHHH	42.65	-
334	Ubiquitination	SAAQNAFKGNQM--- HHHHHHHCCCCC---	55.32	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SCAM1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SCAM1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SCAM1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of SCAM1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.