SBT17_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SBT17_ARATH
• UniProt AC: O65351
• Protein Name: Subtilisin-like protease SBT1.7 {ECO:0000303|PubMed:16193095}
• Gene Name: SBT1.7 {ECO:0000303|PubMed:16193095}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 757
• Subcellular Localization: Secreted, cell wall . Intracellular spaces and cell wall.
• Protein Description: Serine protease. Has a substrate preference for the hydrophobic residues Phe and Ala and the basic residue Asp in the P1 position, and for Asp, Leu or Ala in the P1' position. [PubMed: 12413398 Essential for mucilage release from seed coats. Triggers the accumulation and/or activation of cell wall modifying enzymes necessary either for the loosening of the outer primary cell wall, or to facilitate swelling of the mucilage]
• Protein Sequence: MSSSFLSSTAFFLLLCLGFCHVSSSSSDQGTYIVHMAKSQMPSSFDLHSNWYDSSLRSISDSAELLYTYENAIHGFSTRLTQEEADSLMTQPGVISVLPEHRYELHTTRTPLFLGLDEHTADLFPEAGSYSDVVVGVLDTGVWPESKSYSDEGFGPIPSSWKGGCEAGTNFTASLCNRKLIGARFFARGYESTMGPIDESKESRSPRDDDGHGTHTSSTAAGSVVEGASLLGYASGTARGMAPRARVAVYKVCWLGGCFSSDILAAIDKAIADNVNVLSMSLGGGMSDYYRDGVAIGAFAAMERGILVSCSAGNAGPSSSSLSNVAPWITTVGAGTLDRDFPALAILGNGKNFTGVSLFKGEALPDKLLPFIYAGNASNATNGNLCMTGTLIPEKVKGKIVMCDRGINARVQKGDVVKAAGGVGMILANTAANGEELVADAHLLPATTVGEKAGDIIRHYVTTDPNPTASISILGTVVGVKPSPVVAAFSSRGPNSITPNILKPDLIAPGVNILAAWTGAAGPTGLASDSRRVEFNIISGTSMSCPHVSGLAALLKSVHPEWSPAAIRSALMTTAYKTYKDGKPLLDIATGKPSTPFDHGAGHVSPTTATNPGLIYDLTTEDYLGFLCALNYTSPQIRSVSRRNYTCDPSKSYSVADLNYPSFAVNVDGVGAYKYTRTVTSVGGAGTYSVKVTSETTGVKISVEPAVLNFKEANEKKSYTVTFTVDSSKPSGSNSFGSIEWSDGKHVVGSPVAISWT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
170	N-linked_Glycosylation	GGCEAGTNFTASLCN CCCCCCCCCCHHHCC		-
352	N-linked_Glycosylation	AILGNGKNFTGVSLF EEECCCCCCCCCCCC		-
376	N-linked_Glycosylation	LPFIYAGNASNATNG HCEEEECCCCCCCCC		-
379	N-linked_Glycosylation	IYAGNASNATNGNLC EEECCCCCCCCCCCC		-
460	Phosphorylation	AGDIIRHYVTTDPNP HHCEEEEEECCCCCC		28295753
462	Phosphorylation	DIIRHYVTTDPNPTA CEEEEEECCCCCCCC		28295753
463	Phosphorylation	IIRHYVTTDPNPTAS EEEEEECCCCCCCCE		28295753
468	Phosphorylation	VTTDPNPTASISILG ECCCCCCCCEEEEEE		28295753
470	Phosphorylation	TDPNPTASISILGTV CCCCCCCEEEEEEEE		28295753
472	Phosphorylation	PNPTASISILGTVVG CCCCCEEEEEEEEEC		28295753
542	Phosphorylation	FNIISGTSMSCPHVS EEEEECCCCCCCCHH		24243849
544	Phosphorylation	IISGTSMSCPHVSGL EEECCCCCCCCHHHH		24243849
631	N-linked_Glycosylation	LGFLCALNYTSPQIR HHHHHHHCCCCHHHE		-
644	N-linked_Glycosylation	IRSVSRRNYTCDPSK HEEECCCCCCCCCCC		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SBT17_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SBT17_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SBT17_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of SBT17_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.