| UniProt ID | SAR1B_MOUSE | |
|---|---|---|
| UniProt AC | Q9CQC9 | |
| Protein Name | GTP-binding protein SAR1b | |
| Gene Name | Sar1b | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 198 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Peripheral membrane protein . Golgi apparatus, Golgi stack membrane Peripheral membrane protein . Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region. |
|
| Protein Description | Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex.. | |
| Protein Sequence | MSFIFDWIYSGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHVQARRVWKNYLPAINGIVFLVDCADHERLLESKEELDSLMTDETIANVPILILGNKIDRPEAISEERLREMFGLYGQTTGKGSVSLKELNARPLEVFMCSVLKRQGYGEGFRWMAQYID | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 46 | Acetylation | TTLLHMLKDDRLGQH EEHHHHHCCCCCCCC | 50.43 | 66701433 | |
| 46 | Ubiquitination | TTLLHMLKDDRLGQH EEHHHHHCCCCCCCC | 50.43 | - | |
| 89 | Phosphorylation | ARRVWKNYLPAINGI HHHHHHHHHHHHCEE | 15.44 | - | |
| 143 | Phosphorylation | IDRPEAISEERLREM CCCCHHCCHHHHHHH | 40.22 | 28464351 | |
| 157 | Phosphorylation | MFGLYGQTTGKGSVS HHCCCCCCCCCCCEE | 32.90 | 24759943 | |
| 162 | Phosphorylation | GQTTGKGSVSLKELN CCCCCCCCEEHHHHC | 16.42 | 24759943 | |
| 164 | Phosphorylation | TTGKGSVSLKELNAR CCCCCCEEHHHHCCC | 35.11 | 24719451 | |
| 166 | Ubiquitination | GKGSVSLKELNARPL CCCCEEHHHHCCCCE | 53.28 | - | |
| 178 | S-nitrosocysteine | RPLEVFMCSVLKRQG CCEEEHHHHHHHHCC | 1.40 | - | |
| 178 | S-nitrosylation | RPLEVFMCSVLKRQG CCEEEHHHHHHHHCC | 1.40 | 21278135 | |
| 179 | Phosphorylation | PLEVFMCSVLKRQGY CEEEHHHHHHHHCCC | 20.78 | 23984901 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SAR1B_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SAR1B_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SAR1B_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of SAR1B_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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