SAP47_DROME - dbPTM
SAP47_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SAP47_DROME
UniProt AC Q960T2
Protein Name Synapse-associated protein of 47 kDa
Gene Name Sap47
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 551
Subcellular Localization
Protein Description
Protein Sequence MFSGLTNQFTSLVGAVKGGAGDEDVPAPTGDAPAAAPAASTSVEATASSAVDPEAAAAAGGEGLEGEEAGKRLPKSASLVDSLVSEATGWLGSAKGWLGNASIPSMPAMPSMPSMPAMPAMPSIPSIPGLRKGAGADGAEGAEGAVAGEGGAAASGAVSGGEDDDKSRYISATEGADSHPASGGGTPTGDEGQIGQGKGDEVKITTKVTQQAKHFGSFLSSAISKAGSKIKETVKDNTILDSFNKEQEAFIKGQGGVGNGAAPWIGHANEAKIKEEILGLSQDRRNFVRAPPAGVDFEFSYDTAYPTAIAIMAEDKALETMRFELVPKIITEENFWRNYFYRVSLIIQAAELGTLGADGVGQASSGEDANEVATKEKKSKTAEPAKGDSSVKAIAEQPKAVIEPEAQECDVQAAKSKAKAKAQAGKELGQKISESEFVSDDFQASSESDLAEIQDGMRKLGIDSMTQQALAATDEEQWEKDLEAELKDYEVVDEGGTGGDGGGGRRKGRKAGEDDTEADEDEPTISNLRTRSTNNDWEEYADLIEDTDDLK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
76PhosphorylationAGKRLPKSASLVDSL
HHHCCCCCHHHHHHH		22.5821082442
78PhosphorylationKRLPKSASLVDSLVS
HCCCCCHHHHHHHHH		35.7021082442
153 (in isoform 4)Phosphorylation-12.8728490779
153 (in isoform 3)Phosphorylation-12.8728490779
155 (in isoform 4)Phosphorylation-23.6628490779
155 (in isoform 3)Phosphorylation-23.6628490779
157 (in isoform 4)Phosphorylation-6.9828490779
157 (in isoform 3)Phosphorylation-6.9828490779
159PhosphorylationAAASGAVSGGEDDDK
CCCCCCCCCCCCCCC		40.3127794539
162 (in isoform 4)Phosphorylation-62.8918327897
162 (in isoform 3)Phosphorylation-62.8918327897
166 (in isoform 4)Phosphorylation-43.7718327897
166 (in isoform 3)Phosphorylation-43.7718327897
170 (in isoform 4)Phosphorylation-1.8818327897
170 (in isoform 3)Phosphorylation-1.8818327897
171PhosphorylationDDKSRYISATEGADS
CCCCCEEEECCCCCC		21.8729892262
172 (in isoform 3)Phosphorylation-10.5027794539
172 (in isoform 4)Phosphorylation-10.5027794539
173PhosphorylationKSRYISATEGADSHP
CCCEEEECCCCCCCC		28.3229892262
178PhosphorylationSATEGADSHPASGGG
EECCCCCCCCCCCCC		30.7322817900
182PhosphorylationGADSHPASGGGTPTG
CCCCCCCCCCCCCCC		42.2822817900
186PhosphorylationHPASGGGTPTGDEGQ
CCCCCCCCCCCCCCC		22.4319429919
188PhosphorylationASGGGTPTGDEGQIG
CCCCCCCCCCCCCCC		58.0419429919
194 (in isoform 4)Phosphorylation-7.0027794539
194 (in isoform 3)Phosphorylation-7.0027794539
217PhosphorylationQQAKHFGSFLSSAIS
HHHHHHHHHHHHHHH		23.2821082442
220PhosphorylationKHFGSFLSSAISKAG
HHHHHHHHHHHHHHC		18.7321082442
221PhosphorylationHFGSFLSSAISKAGS
HHHHHHHHHHHHHCH		31.5921082442
224PhosphorylationSFLSSAISKAGSKIK
HHHHHHHHHHCHHHH		19.0321082442
242PhosphorylationKDNTILDSFNKEQEA
CCCCCHHHCCHHHHH		27.5527794539
354PhosphorylationIQAAELGTLGADGVG
HHHHHHCCCCCCCCC		34.3419429919
364PhosphorylationADGVGQASSGEDANE
CCCCCCCCCCCCHHH		30.8719429919
365PhosphorylationDGVGQASSGEDANEV
CCCCCCCCCCCHHHH		49.5719429919
433PhosphorylationKELGQKISESEFVSD
HHHHHHHCHHHCCCC		41.9518327897
464PhosphorylationMRKLGIDSMTQQALA
HHHHCCCHHHHHHHH		23.0822817900
516PhosphorylationRKAGEDDTEADEDEP
CCCCCCCCCCCCCCC		45.4519429919
524PhosphorylationEADEDEPTISNLRTR
CCCCCCCCCCCCCCC		34.6818511481
530PhosphorylationPTISNLRTRSTNNDW
CCCCCCCCCCCCCCH		31.9419060867
532PhosphorylationISNLRTRSTNNDWEE
CCCCCCCCCCCCHHH		34.5719429919
533PhosphorylationSNLRTRSTNNDWEEY
CCCCCCCCCCCHHHH		34.4519429919
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SAP47_DROME !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SAP47_DROME !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SAP47_DROME !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SAP47_DROME

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of Drosophila melanogaster embryos.";
Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.;
J. Proteome Res. 7:1675-1682(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-178; SER-182; THR-186;SER-433 AND THR-530, AND MASS SPECTROMETRY.

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