dbPTM

SAMH1_CHICK - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SAMH1_CHICK
UniProt AC	Q5ZJL9
Protein Name	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Gene Name	SAMHD1
Organism	Gallus gallus (Chicken).
Sequence Length	614
Subcellular Localization	Nucleus.
Protein Description	Host restriction nuclease that blocks early-stage virus replication. May function by reducing the cellular dNTP levels to levels too low for viral reverse transcription to occur (By similarity)..
Protein Sequence	MGSPAAGWGAAPAKRARREGSAESSCGSPADRDPRLWDTERLCQHLSRNGVGEPGLLRRFRESGVTGAMLLDLPACALRITHACLPDERLEVLACLNQLRQTADIMKVFNDPVHGHIEIHPLLVRIIDTPQFQRLRYIKQLGGTYFVFPGASHNRFEHSLGVGYLAGCLVRELKERQPELDITQRDILCVEIAGLCHDLGHGPFSHMFDGRFIPLARQGLNWKHETASVEMFEHLITSNKLEEIMESYGLILEEDIAFIKEQIGGPIDETACEESWPYRGRPKEKSFLYEIVANKKNGIDVDKWDYFARDCHHLGIQNNFDYRRLIKFTRVCEAGNQKHICARDKEVGNLYDMFHTRNCLHRRAYQHKVGNIIEIMITEAFQKADCFFQIEGSKGKLYHISTAMEDMEAYTKLTDNIYLEILHSSRPELSEAREILHKIERRELYKFLGETQPEKVNEIPKDEYDGLAGDIANSKPEKDPPDVELTAEDFIVDVVNMDYGMKDQNPIDNVLFYCKADPSKAIKVSKEQVSRLLPGTFSEQVIRVYCKRQDPIIVSAAKQYFVQWCIKRDFTKPQDGDVVAPHLTPLKQSWNNRSKTEYTTASEPSCKQKLSFNK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of SAMH1_CHICK !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SAMH1_CHICK !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SAMH1_CHICK !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SAMH1_CHICK !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of SAMH1_CHICK !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SAMH1_CHICK

Related Literatures of Post-Translational Modification