SALL2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SALL2_MOUSE
• UniProt AC: Q9QX96
• Protein Name: Sal-like protein 2
• Gene Name: Sall2
• Organism: Mus musculus (Mouse).
• Sequence Length: 1004
• Subcellular Localization: Nucleus .
• Protein Description: Probable transcription factor that plays a role in eye development before, during, and after optic fissure closure..
• Protein Sequence: MSRRKQRRPQQLISDCEGPSASENGDASEEDHPQVCAKCCAQFSDPTEFLAHQNSCCTDPPVMVIIGGQENPSNSSASSAPRPEGHSRSQVMDTEHSNPPDSGSSGAPDPTWGPERRGEESSGQFLVAATGTAAGGGGGLILASPKLGATPLPPESTPAPPPPPPPPPPPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPGTGAASSTKPLLPLFSPIKPAQTGKTLASSSSSSSSSGAEPPKQAFFHLYHPLGSQHPFSVGGVGRSHKPTPAPSPALPGSTDQLIASPHLAFPGTTGLLAAQCLGAARGLEAAASPGLLKPKNGSGELGYGEVISSLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAGTPGGGVERKPLVASTTALSATESLTLLSTGTSTAVAPGLPTFNKFVLMKAVEPKSKADENTPPGSEGSAIAGVADSGSATRMQLSKLVTSLPSWALLTNHLKSTGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVASTASGAPTTSAPAPSSSASGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKTSPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIPNGGSALSEGGGAAQENSSEQSTASGPGSFPQPQSQQPSPEEEMSEEEEEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSEEVSGAEEEVATSVAAPTTVKEMDSNEKAPQHTLPPPPPPPDNLDHPQPMEQGTSDVSGAMEEEAKLEGTSSPMAALTQEGEGTSTPLVEELNLPEAMKKDPGESSGRKACEVCGQSFPTQTALEEHQKTHPKDGPLFTCVFCRQGFLDRATLKKHMLLAHHQVPPFAPHGPQNIATLSLVPGCSSSIPSPGLSPFPRKDDPTMP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
243	Phosphorylation	KPLLPLFSPIKPAQT CCCCCCCCCCCCCCC	33.14	-
343	Phosphorylation	RGLEAAASPGLLKPK HCHHHHHCCCCCCCC	18.12	28066266
348	Malonylation	AASPGLLKPKNGSGE HHCCCCCCCCCCCCC	60.01	26073543
639	Phosphorylation	VICLRVLSCPRALRL EEEEEECCCCCHHHC	21.15	22324799
794	Phosphorylation	SGGEKAISVRGDSEE CCCCCEEEECCCCHH	15.60	29899451
799	Phosphorylation	AISVRGDSEEVSGAE EEEECCCCHHCCCCH	38.18	21149613
803	Phosphorylation	RGDSEEVSGAEEEVA CCCCHHCCCCHHHHH	35.25	15345747
811	Phosphorylation	GAEEEVATSVAAPTT CCHHHHHHHCCCCCC	28.98	29899451
812	Phosphorylation	AEEEVATSVAAPTTV CHHHHHHHCCCCCCH	10.46	29899451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SALL2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SALL2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SALL2_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of SALL2_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.