| UniProt ID | SAHH_CAEEL | |
|---|---|---|
| UniProt AC | P27604 | |
| Protein Name | Adenosylhomocysteinase | |
| Gene Name | ahcy-1 | |
| Organism | Caenorhabditis elegans. | |
| Sequence Length | 437 | |
| Subcellular Localization | ||
| Protein Description | Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.. | |
| Protein Sequence | MAQSKPAYKVADIKLADFGRKEIILAENEMPGLMAMRSKYGPSQPLKGARIAGCLHMTIQTAVLIETLTALGAEVQWSSCNIFSTQDHAAAAIAQTGVPVYAWKGETDEEYEWCIEQTIVFKDGQPLNMILDDGGDLTNLVHAKYPQYLAGIRGLSEETTTGVHNLAKMLAKGDLKVPAINVNDSVTKSKFDNLYGIRESLPDGIKRATDVMLAGKVAVVAGYGDVGKGSAASLKAFGSRVIVTEIDPINALQAAMEGYEVTTLEEAAPKANIIVTTTGCKDIVTGKHFELLPNDAIVCNVGHFDCEIDVKWLNTNATKKDTIKPQVDRYTLKNGRHVILLAEGRLVNLGCATGHPSFVMSNSFTNQVLAQVELWTKFGTPQEYKLGLYVLPKTLDEEVAYLHLAQLGVKLTKLSDEQASYLGVPVAGPYKPDHYRY | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 156 | Phosphorylation | LAGIRGLSEETTTGV HHHCCCCCCCCCCHH | 35.89 | 21082442 | |
| 185 | Phosphorylation | PAINVNDSVTKSKFD CEEECCCCCCHHHCC | 26.87 | 28854356 | |
| 187 | Phosphorylation | INVNDSVTKSKFDNL EECCCCCCHHHCCCC | 33.29 | 19530675 | |
| 189 | Phosphorylation | VNDSVTKSKFDNLYG CCCCCCHHHCCCCCC | 29.23 | 22923814 | |
| 195 | Phosphorylation | KSKFDNLYGIRESLP HHHCCCCCCHHHHCC | 19.43 | 27067626 | |
| 401 | Phosphorylation | TLDEEVAYLHLAQLG CCCHHHHHHHHHHHC | 10.38 | 28854356 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SAHH_CAEEL !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SAHH_CAEEL !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SAHH_CAEEL !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of SAHH_CAEEL !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
