dbPTM

SAC7_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SAC7_ARATH
UniProt AC	Q9C5G5
Protein Name	Phosphoinositide phosphatase SAC7
Gene Name	SAC7
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	597
Subcellular Localization	Endoplasmic reticulum membrane Multi-pass membrane protein . Cytoplasmic vesicle membrane Multi-pass membrane protein . Associated to tip-localized membranes in growing root hairs (PubMed:18281508).
Protein Description	Phosphoinositide phosphatase that preferentially hydrolyzes PtdIns(4)P. Regulates the accumulation of PtdIns(4)P on membrane compartments at the tips of growing root hairs leading to proper root hair development..
Protein Sequence	METVDSRNKLHSRLRLWEFPDQYIIEPADGSGSSCLDISRVDASMKLIDQVPESNSVRVPKIRSIFGVVGMLKLLAGSYLVVVTESERVGSFLGHPIFKVTTLKVLPCDHSLKNSPEEQKKMETEFSKLLSVAEKTTGLYFSYEVNLTLSSQRLHEMGDESKSLPLWRQAEPRFLWNNYMLEVLIDNKLDQFLLPVIQGSFNSFETAIGRDIVDITLIARRCTRRNGTRMWRRGADLDGYVANFVETEQIVQMNGYTSSFVQVRGSMPFMWEQVVDLTYKPKFEIVQPEEAKRIAERHFLDLRKKYGSVLAVDLVNKQGGEGRLCEKYATVMQHITGDDIRYLHFDFHQICGHIHFERLSILYEQIEGFLEKNGYFLLNEKGEKMKEQLGVVRSNCIDCLDRTNVTQSMIGRKMLEVQLKRIGVFGAEETISSHLNFDEHYKILWANHGDEISIQYSGTPALKGDFVRYGHRTAHGVLKDGWSSLRRYYLNNFADGTKQDAIDLLQGHYIVAVSRDMAPVPQKGGLEAVANFPVALFVVLMSFWFATMSLKQTGSDYKHKHLFFSLLWTGICVGMAALVRANGRIFCNRPRLHKPRG

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
127	Phosphorylation	KKMETEFSKLLSVAE HHHHHHHHHHHHHHH	19880383
308	Phosphorylation	DLRKKYGSVLAVDLV HHHHHHCCEEEEECC	19880383
360	Phosphorylation	HIHFERLSILYEQIE CCHHHHHHHHHHHHH	19880383
403	Phosphorylation	CIDCLDRTNVTQSMI HHHHHHHCCCCHHHH	22074104

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SAC7_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SAC7_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SAC7_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of SAC7_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SAC7_ARATH

Related Literatures of Post-Translational Modification