SAC5_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SAC5_ARATH
• UniProt AC: Q8RW97
• Protein Name: Phosphoinositide phosphatase SAC5
• Gene Name: SAC5
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 785
• Subcellular Localization: Vacuole membrane; Peripheral membrane protein.
• Protein Description: The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)..
• Protein Sequence: MGSEPRFEPRPELIDLPVLQKFKLYATPSNFYLIGRDENKSFRRILKIDRRDQNELNLFEDPTRYTKDEMRELKRRMIVGNEESGGFKAITTCYGIIGFVRFLEPYYMLLITKRKKVGEICGHTVYGIAESQMIAIPHPSIQSKVAKSEAELRYKKLLSVVDLSKNFYFSYTYHLMYSLQKNIGNTERGNPHDNTMFVWNSFLTREIRKILQNSIWTVALIYGFFQQTKCSVSGEKFVFTIIARRSRHYAGTRYLRRGVNDIGRVANDVETEQIVSKVVPAGQKIPITSVVQVRGSIPLFWSQEASVFNPQPEIILNKKDANYEATQHHFQNLRQRYGNRIIILNLLKTVTGEKKHRETILRGEFAKTIRFINKGMDREHRLKAIHFDLSKHYKKGADGAFNHLCIFSRKSLELTDLFYCKAPSGVGAEEVIYDSFFNNPIPSQDEEASSPEKEDMKADIFLLQNGVLRTNCIDCLDRTNFAQYAHGLVSLGHQLRTLGISGPPVVDLNNPLAIELMDAYQKMGNTLAMQYGGSEAHSKMFCDLRGNWNMVMRQRDIFTAVRRYYSNAYQDSDKQNAINVFLGHFRPRLGRPALWELDSDQHNIGRSGSNLDIENMRPLIRRSFSDNIIMDCDLNLEELVRENSQPTYEGLNGGVSGTNLEFPFYETEPASLSFLSVMRNEELMRETGSGQMFQGSSSNSDSHRPNDIPGFSHSYVTKFTPAEDIFERGSSKSVSSDNLFTDRDESVTSLTNTNSSFEFPIMGGSDLLPGFSNAFARWVFSARAW

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
106	Phosphorylation	FVRFLEPYYMLLITK HHHHHHHHHHHHHCC		24924143
107	Phosphorylation	VRFLEPYYMLLITKR HHHHHHHHHHHHCCC		24924143
112	Phosphorylation	PYYMLLITKRKKVGE HHHHHHHCCCCCHHH		24924143
564	Phosphorylation	IFTAVRRYYSNAYQD HHHHHHHHHHHCCCC		30407730
565	Phosphorylation	FTAVRRYYSNAYQDS HHHHHHHHHHCCCCC		30407730
566	Phosphorylation	TAVRRYYSNAYQDSD HHHHHHHHHCCCCCC		30407730
569	Phosphorylation	RRYYSNAYQDSDKQN HHHHHHCCCCCCHHH		30407730
607	Phosphorylation	DQHNIGRSGSNLDIE CCCCCCCCCCCCCHH		25561503
609	Phosphorylation	HNIGRSGSNLDIENM CCCCCCCCCCCHHHC		30589143
730	Phosphorylation	EDIFERGSSKSVSSD HHHHHCCCCCCCCCC		23111157
731	Phosphorylation	DIFERGSSKSVSSDN HHHHCCCCCCCCCCC		30407730

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SAC5_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SAC5_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SAC5_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of SAC5_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.