SAA1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SAA1_HUMAN
• UniProt AC: P0DJI8
• Protein Name: Serum amyloid A-1 protein
• Gene Name: SAA1
• Organism: Homo sapiens (Human).
• Sequence Length: 122
• Subcellular Localization: Secreted .
• Protein Description: Major acute phase protein..
• Protein Sequence: MKLLTGLVFCSLVLGVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
17	Phosphorylation	CSLVLGVSSRSFFSF HHHHHCCCCHHHHHH	20.45	29978859
18	Phosphorylation	SLVLGVSSRSFFSFL HHHHCCCCHHHHHHH	29.54	28509920
47	Phosphorylation	SDMREANYIGSDKYF HHHHHHCCCCCCCCH	17.44	29083192
50	Phosphorylation	REANYIGSDKYFHAR HHHCCCCCCCCHHCC	22.75	29083192
53	Phosphorylation	NYIGSDKYFHARGNY CCCCCCCCHHCCCCH	12.94	-
77	Phosphorylation	VWAAEAISDARENIQ CHHHHHHHHHHHHHH	32.06	-
94	Phosphorylation	FGHGAEDSLADQAAN HCCCCHHHHHHHHHH	19.57	27251275
101	"N4,N4-dimethylasparagine"	SLADQAANEWGRSGK HHHHHHHHHHHHCCC	48.87	-
101	Methylation	SLADQAANEWGRSGK HHHHHHHHHHHHCCC	48.87	8783012
106	Phosphorylation	AANEWGRSGKDPNHF HHHHHHHCCCCCCCC	46.38	27251275
122	Phosphorylation	PAGLPEKY------- CCCCCCCC-------	23.33	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SAA1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SAA1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SAA1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of SAA1_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.