S41A2_HUMAN - dbPTM
S41A2_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID S41A2_HUMAN
UniProt AC Q96JW4
Protein Name Solute carrier family 41 member 2
Gene Name SLC41A2
Organism Homo sapiens (Human).
Sequence Length 573
Subcellular Localization Cell membrane
Multi-pass membrane protein .
Protein Description Acts as a plasma-membrane magnesium transporter..
Protein Sequence MTNSKGRSITDKTSGGPSSGGGFVDWTLRLNTIQSDKFLNLLLSMVPVIYQKNQEDRHKKANGIWQDGLSTAVQTFSNRSEQHMEYHSFSEQSFHANNGHASSSCSQKYDDYANYNYCDGRETSETTAMLQDEDISSDGDEDAIVEVTPKLPKESSGIMALQILVPFLLAGFGTVSAGMVLDIVQHWEVFRKVTEVFILVPALLGLKGNLEMTLASRLSTAVNIGKMDSPIEKWNLIIGNLALKQVQATVVGFLAAVAAIILGWIPEGKYYLDHSILLCSSSVATAFIASLLQGIIMVGVIVGSKKTGINPDNVATPIAASFGDLITLAILAWISQGLYSCLETYYYISPLVGVFFLALTPIWIIIAAKHPATRTVLHSGWEPVITAMVISSIGGLILDTTVSDPNLVGIVVYTPVINGIGGNLVAIQASRISTYLHLHSIPGELPDEPKGCYYPFRTFFGPGVNNKSAQVLLLLVIPGHLIFLYTIHLMKSGHTSLTIIFIVVYLFGAVLQVFTLLWIADWMVHHFWRKGKDPDSFSIPYLTALGDLLGTALLALSFHFLWLIGDRDGDVGD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
13PhosphorylationGRSITDKTSGGPSSG
CCCCCCCCCCCCCCC		35.1024732914
14PhosphorylationRSITDKTSGGPSSGG
CCCCCCCCCCCCCCC		47.7124732914
15UbiquitinationSITDKTSGGPSSGGG
CCCCCCCCCCCCCCC		58.2123000965
18PhosphorylationDKTSGGPSSGGGFVD
CCCCCCCCCCCCCCC		44.9124732914
19PhosphorylationKTSGGPSSGGGFVDW
CCCCCCCCCCCCCCE		44.5924732914
27PhosphorylationGGGFVDWTLRLNTIQ
CCCCCCEEEECCCCC		9.5024732914
44PhosphorylationKFLNLLLSMVPVIYQ
HHHHHHHHHHHHHHH		20.08-
112PhosphorylationCSQKYDDYANYNYCD
CCHHCCCCCCCCCCC		8.2127259358
115PhosphorylationKYDDYANYNYCDGRE
HCCCCCCCCCCCCCC		10.1924961811
117PhosphorylationDDYANYNYCDGRETS
CCCCCCCCCCCCCCC		4.9927642862
123PhosphorylationNYCDGRETSETTAML
CCCCCCCCCCCCHHH		30.4225841592
124PhosphorylationYCDGRETSETTAMLQ
CCCCCCCCCCCHHHC		28.3525841592
126PhosphorylationDGRETSETTAMLQDE
CCCCCCCCCHHHCCC		21.4425841592
127PhosphorylationGRETSETTAMLQDED
CCCCCCCCHHHCCCC		13.1525841592
136PhosphorylationMLQDEDISSDGDEDA
HHCCCCCCCCCCCCC		34.4026657352
137PhosphorylationLQDEDISSDGDEDAI
HCCCCCCCCCCCCCE		46.0425137130
148PhosphorylationEDAIVEVTPKLPKES
CCCEEEECCCCCCCC		10.9528102081
213PhosphorylationLKGNLEMTLASRLST
CCCCHHHHHHHHHHH		15.14-
220PhosphorylationTLASRLSTAVNIGKM
HHHHHHHHHHHHCCC		38.9425921289
226UbiquitinationSTAVNIGKMDSPIEK
HHHHHHCCCCCHHHH		35.4223000965
229PhosphorylationVNIGKMDSPIEKWNL
HHHCCCCCHHHHHHH		25.0325921289
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of S41A2_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of S41A2_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of S41A2_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
KASH5_HUMANCCDC155physical
25416956
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of S41A2_HUMAN

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Related Literatures of Post-Translational Modification

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