| UniProt ID | S41A1_HUMAN | |
|---|---|---|
| UniProt AC | Q8IVJ1 | |
| Protein Name | Solute carrier family 41 member 1 | |
| Gene Name | SLC41A1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 513 | |
| Subcellular Localization |
Cell membrane Multi-pass membrane protein. |
|
| Protein Description | Acts as a magnesium transporter that is responsive to magnesium balance.. | |
| Protein Sequence | MSSKPEPKDVHQLNGTGPSASPCSSDGPGREPLAGTSEFLGPDGAGVEVVIESRANAKGVREEDALLENGSQSNESDDVSTDRGPAPPSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGHMDTPKELWRMITGNMALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGVIIGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYLELNHWRYIYPLVCAFFVALLPVWVVLARRSPATREVLYSGWEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTFLHMNGMPGENSEQAPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGHLVFLYTISCMQGGHTTLTLIFIIFYMTAALLQVLILLYIADWMVHWMWGRGLDPDNFSIPYLTALGDLLGTGLLALSFHVLWLIGDRDTDVGD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 16 | Phosphorylation | DVHQLNGTGPSASPC CHHHCCCCCCCCCCC | 44.86 | 28985074 | |
| 36 | Phosphorylation | GREPLAGTSEFLGPD CCCCCCCCCCCCCCC | 21.34 | 24247654 | |
| 71 | Phosphorylation | DALLENGSQSNESDD HHHHHCCCCCCCCCC | 41.85 | 25921289 | |
| 73 | Phosphorylation | LLENGSQSNESDDVS HHHCCCCCCCCCCCC | 44.24 | 25159151 | |
| 76 | Phosphorylation | NGSQSNESDDVSTDR CCCCCCCCCCCCCCC | 43.28 | 20363803 | |
| 80 | Phosphorylation | SNESDDVSTDRGPAP CCCCCCCCCCCCCCC | 31.42 | 24144214 | |
| 81 | Phosphorylation | NESDDVSTDRGPAPP CCCCCCCCCCCCCCC | 29.57 | 28102081 | |
| 89 | Phosphorylation | DRGPAPPSPLKETSF CCCCCCCCCCCCCCC | 41.63 | 25159151 | |
| 152 | Phosphorylation | LKGNLEMTLASRLST CCCCHHHHHHHHHHH | 15.14 | - | |
| 159 | Phosphorylation | TLASRLSTAANIGHM HHHHHHHHHHHCCCC | 34.09 | - | |
| 170 | Ubiquitination | IGHMDTPKELWRMIT CCCCCCHHHHHHHHH | 68.48 | 21890473 | |
| 309 | Phosphorylation | WVVLARRSPATREVL HHHHHCCCCCHHHHH | 17.21 | 22798277 | |
| 312 | Phosphorylation | LARRSPATREVLYSG HHCCCCCHHHHHHCC | 30.65 | 22798277 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of S41A1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of S41A1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of S41A1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of S41A1_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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