| UniProt ID | S27A1_MOUSE | |
|---|---|---|
| UniProt AC | Q60714 | |
| Protein Name | Long-chain fatty acid transport protein 1 {ECO:0000305} | |
| Gene Name | Slc27a1 {ECO:0000312|MGI:MGI:1347098} | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 646 | |
| Subcellular Localization |
Cell membrane Single-pass membrane protein . Endomembrane system Single-pass membrane protein . Cytoplasm . Plasma membrane and intracellular membranes, at least in adipocytes (PubMed:10593920, PubMed:11970897, PubMed:28178239). In adipocytes, bu |
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| Protein Description | Mediates the ATP-dependent import of long-chain fatty acids (LCFA) into the cell by mediating their translocation at the plasma membrane. [PubMed: 7954810] | |
| Protein Sequence | MRAPGAGTASVASLALLWFLGLPWTWSAAAAFCVYVGGGGWRFLRIVCKTARRDLFGLSVLIRVRLELRRHRRAGDTIPCIFQAVARRQPERLALVDASSGICWTFAQLDTYSNAVANLFRQLGFAPGDVVAVFLEGRPEFVGLWLGLAKAGVVAALLNVNLRREPLAFCLGTSAAKALIYGGEMAAAVAEVSEQLGKSLLKFCSGDLGPESILPDTQLLDPMLAEAPTTPLAQAPGKGMDDRLFYIYTSGTTGLPKAAIVVHSRYYRIAAFGHHSYSMRAADVLYDCLPLYHSAGNIMGVGQCVIYGLTVVLRKKFSASRFWDDCVKYNCTVVQYIGEICRYLLRQPVRDVEQRHRVRLAVGNGLRPAIWEEFTQRFGVPQIGEFYGATECNCSIANMDGKVGSCGFNSRILTHVYPIRLVKVNEDTMEPLRDSEGLCIPCQPGEPGLLVGQINQQDPLRRFDGYVSDSATNKKIAHSVFRKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEAVLSRLLGQTDVAVYGVAVPGVEGKAGMAAIADPHSQLDPNSMYQELQKVLASYARPIFLRLLPQVDTTGTFKIQKTRLQREGFDPRQTSDRLFFLDLKQGRYVPLDERVHARICAGDFSL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 80 | S-nitrosocysteine | RAGDTIPCIFQAVAR HCCCHHHHHHHHHHH | 4.26 | - | |
| 80 | S-nitrosylation | RAGDTIPCIFQAVAR HCCCHHHHHHHHHHH | 4.26 | 21278135 | |
| 170 | S-nitrosocysteine | RREPLAFCLGTSAAK CCCCCHHHHCCHHHH | 2.59 | - | |
| 170 | S-nitrosylation | RREPLAFCLGTSAAK CCCCCHHHHCCHHHH | 2.59 | 21278135 | |
| 406 | S-nitrosocysteine | MDGKVGSCGFNSRIL CCCCCCCCCCCHHCC | 6.24 | - | |
| 406 | S-nitrosylation | MDGKVGSCGFNSRIL CCCCCCCCCCCHHCC | 6.24 | 21278135 | |
| 466 | Phosphorylation | PLRRFDGYVSDSATN CHHHCCCCCCCHHCC | 9.91 | 28066266 | |
| 468 | Phosphorylation | RRFDGYVSDSATNKK HHCCCCCCCHHCCCH | 19.84 | 27180971 | |
| 470 | Phosphorylation | FDGYVSDSATNKKIA CCCCCCCHHCCCHHH | 29.50 | 28066266 | |
| 472 | Phosphorylation | GYVSDSATNKKIAHS CCCCCHHCCCHHHHH | 52.07 | 28066266 | |
| 474 | Ubiquitination | VSDSATNKKIAHSVF CCCHHCCCHHHHHHH | 41.00 | - | |
| 567 | Phosphorylation | HSQLDPNSMYQELQK HHCCCCCHHHHHHHH | 25.01 | 28059163 | |
| 579 | Phosphorylation | LQKVLASYARPIFLR HHHHHHHCHHHHHHH | 10.87 | 28059163 | |
| 624 | Ubiquitination | RLFFLDLKQGRYVPL EEEEEECCCCCEEEC | 50.83 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of S27A1_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of S27A1_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of S27A1_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of S27A1_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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