S26A1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: S26A1_HUMAN
• UniProt AC: Q9H2B4
• Protein Name: Sulfate anion transporter 1
• Gene Name: SLC26A1
• Organism: Homo sapiens (Human).
• Sequence Length: 701
• Subcellular Localization: Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane .
• Protein Description: Mediates sulfate transport with high affinity. [PubMed: 12713736 Mediates oxalate transport]
• Protein Sequence: MDESPEPLQQGRGPVPVRRQRPAPRGLREMLKARLWCSCSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLDAGCMAARRKEGGSETGVGEGGPAQGEDLGPVSTRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTARARHRELEATDAHL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MDESPEPLQQG ----CCCCCCHHHCC	30.24	28857561
158	N-linked_Glycosylation	DGLQPGANSSTLNGS CCCCCCCCCCCCCCC	42.27	UniProtKB CARBOHYD
163	N-linked_Glycosylation	GANSSTLNGSAAMLD CCCCCCCCCCHHHHC	42.32	UniProtKB CARBOHYD
467	Phosphorylation	LPRLWRMSPADALVW CCHHHCCCHHHHHHH	14.36	-
500	Phosphorylation	GVILSLLSLAGRTQR HHHHHHHHHCCCCCC	22.82	24719451
578	Phosphorylation	ARRKEGGSETGVGEG HHHCCCCCCCCCCCC	42.73	28258704
580	Phosphorylation	RKEGGSETGVGEGGP HCCCCCCCCCCCCCC	38.57	28258704
598	Phosphorylation	EDLGPVSTRAALVPA CCCCCCCHHHHHHHH	25.26	28857561

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of S26A1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of S26A1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of S26A1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of S26A1_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.